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引用本文:简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.
通信作者:邓呈亮,Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
Athina Stamati1 · Athanasios Christoforidis2
Received: 7 October 2024 / Accepted: 31 December 2024 / Published online: 10 January 2025 © The Author(s) 2025
Abstract
Aims To assess the efficacy and safety of automated insulin delivery (AID) systems compared to standard care in managing glycaemic control during pregnancy in women with Type 1 Diabetes Mellitus (T1DM).
Methods We searched MEDLINE, Cochrane Library, registries and conference abstracts up to June 2024 for randomized controlled trials (RCTs) and observational studies comparing AID to standard care in pregnant women with T1DM. We con-ducted random effects meta-analyses for % of 24-h time in range of 63–140 mg/dL (TIR), time in hyperglycaemia (>140 mg/ dl and>180 mg/dL), hypoglycaemia (<63 mg/dl and<54 mg/dL), total insulin dose (units/kg/day), glycemic variability (%), changes in HbA1c (%), maternal and fetal outcomes.
Results Thirteen studies (450 participants) were included. AID significantly increased TIR (Mean difference, MD 7.01%, 95% CI 3.72–10.30) and reduced time in hyperglycaemia>140 mg/dL and>180 mg/dL (MD – 5.09%, 95% CI – 9.41 to – 0.78 and MD – 2.44%, 95% CI – 4.69 to – 0.20, respectively). Additionally, glycaemic variability was significantly reduced (MD – 1.66%, 95% CI – 2.73 to – 0.58). Other outcomes did not differ significantly.
Conclusion AID systems effectively improve glycaemic control during pregnancy in women with T1DM by increasing TIR and reducing hyperglycaemia without any observed adverse short-term effects on maternal and fetal outcomes.
Keywords Automated insulin delivery · Pregnancy · Type 1 diabetes mellitus · Systematic review · Meta-analysis
A mobile application for wound care (Minuteful) was trailed over a seven-month period in an acute inpatient setting in Northwest England. During the trial an increase in the availability of wound photography was noted (+37%), a reduction in inappropriate tissue viability nurse reviews (-10%) and the identification of mis-reported pressure ulcers (n=65). Challenges noted during the implementation included initial software compatibility issues with the tablets available on the wards and poor staff engagement. Overall, this initial trial indicates the potential safety, economic and service efficiency improvements that may be possible via implementation of mobile application technology in wound care. Further robust studies are needed to explore the initial findings of this trial in greater depth.
KEY WORDS: Acute care Chronic wounds Mobile application Wound care
MATTHEW WYNN
Honorary Tissue Viability Nurse- Northern Care Alliance NHS Foundation Trust' LUCY SCHOLES Senior Tissue Viability Nurse, Northern Care Alliance NHS Foundation Trust 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
Emily R. Kindal1, Kaitlin J. Larson2, Luis G. Fernandez3,4,5#, Sean F. O’Keefe6, Marc R. Matthews7*
1 Medical Student IV, Royal College of Surgeons in Ireland, Dublin, Ireland
2 Surgical Resident, The Arrowhead Surgical Residency, Glendale, Arizona
3 Department of Surgery, University of Texas Health Science Center, Tyler, USA
4 Trauma Wound Care, UT Health East, Tyler, USA
5 Department of Surgery, University of Texas Medical Branch, Galveston, USA
6 Business Development Manager, Saint Paul, US
7 University of Arizona & Creighton University Schools of Medicine, The Arizona Burn Center, Phoenix, Arizona
Email:★marc_该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。.
How to cite this paper: Kindal, E.R., Larson, K.J., Fernandez, L.G., O’Keefe, S.F. and Matthews, M.R. (2022) The Use of the V.A.C. RX-4 for Multiple Soft Tissue Wound Application in the Single Patient: A Case Report. Surgical Science, 13, 155-163. https://doi.org/10.4236/ss.2022.133020
Received: January 28, 2022
Accepted: March 26, 2022
Published: March 29, 2022
Copyright © 2022 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/
Contact burn injuries account for a considerable proportion of admissions that frequently require debridement. Such debridements of these multiple open wounds might benefit from the application of negative pressure wound therapy (NPWT) for the removal of proinflammatory mediators and to promote granulation tissue with macrostrain and microstrain. Having four or more Vacuum Assist Closure (V.A.C.) Ulta devices connected to the same patient for adequate wound coverage is cumbersome in the management of the patient’s wound care and tethers the patient to the bed. The V.A.C. RX-4 is a multichannel device that can deliver NPWT with a smaller footprint. In addition, the V.A.C. RX-4 has a weight of 16 lbs. versus one V.A.C Ulta which is 7.4 lbs. Therefore, collectively, four V.A.C. Ultas would equal 29.6 lbs. or almost double the weight of a single V.A.C. RX-4. Use of the V.A.C. RX-4 by healthcare providers can mean greater mobility for the patient and easier transport between patient destinations within the hospital. This case report demonstrates the utility of the V.A.C. RX-4 for open and freshly debrided, large soft tissue wounds in a burn patient.
# UT Texas, Assistant Clinical Professor of Surgery/Family Practice UT Health North East, Tyler, Texas, Adjunct Clinical Professor of Medicine and Nursing, University of Texas, Arlington, Texas, Past Commanding General TXSG Medical Brigade, Austin, TX USA, Chairman Emeritus, Division of Trauma Surgery/Surgical Critical Care, Associate Trauma Medical Director and Chief of Trauma Surgical Critical Care Unit, Christus Trinity Mother Frances Health System, Tyler, Texas, Surgical Attending, Adjunct Associate Professor, University of North Texas, Denton, Texas.
Keywords
V.A.C. RX-4, Negative Pressure Wound Therapy, Wounds, V.A.C. Ulta, Footprint, Burns
Nanotechnology has opened a new area of scientific research. This field deals with materials within the dimensions of 1–100nm and a plethora of new technologies have emerged. In wound care, silver nanoparticles are used to aid wound healing as an antimicrobial agent, but also as an anti-inflammatory agent. The properties of silver nanoparticles differ from that of the material on a larger scale and their production can be controlled to give varied properties and characteristics that have different uses. These resultant properties are very important and differences in characterisation can alter their biological and physical attributes. All wound dressings have to undergo rigorous scrutiny around toxicity and safety when regulatory review is undertaken, yet some users still have concerns over long-term effects of silver nanoparticles in vivo. This review will address some of these concerns and reviews the current health and safety data associated with introduction of new products containing silver nanoparticles using Venus Ag dressings (SFM LTD, UK) as an example.
KEY WORDS Nanoparticles of silver Safety Silver dressings Toxicity
VAL EDWARDS-JONES PhD,CSci, FIBMS, Independent Microbiology Consultant, Essential Microbiology Limited
There were an estimated 3.8 million patients with a wound managed by the NHS in 2017/2018 at a cost of £8.3 billion (Guest et al, 2017). The cost to the patient and their quality of life is immense. Evidence has shown that there are wide variations in the care of people with chronic wounds, with many patients not receiving the correct assessment or a diagnosis on which to base decisions about their care (Guest et al, 2015; Gray et al, 2018). Delivering efficient and effective care to patients with a venous leg ulcer (VLU) requires collaborative working across specialist and community settings to tackle inequalities in care, improve outcomes, enhance productivity, and provide value for money.
KEY WORDS Venous leg ulcer Compression Reducing variation UrgoKTwo DR CAROLINE DOWSETT Clinical Nurse Specialist Tissue Viability, East London NHS Foundation Trust; Independent Nurse Consultant
ABSTRACT: Biofilm formation in wounds contributes greatly to the lack of healing and increased healthcare expenditures. Antimicrobial efficacy is decreased significantly in the presence of biofilms, which can, in turn, promote the development of antibiotic resistance. Antibiofilm strategies to prevent the formation and persistence of biofilm in wounds would consequently decrease the incidence of chronic wounds and improve wound healing. The use of preclinical biofilm models to assess the antibiofilm efficacy of wound dressings is a prerequisite to identifying new technologies that can improve outcomes in hardto-heal wounds. Improvements to preclinical approaches (in vitro and in vivo) to biofilm models are needed. Living tissue (ex vivo) derived from pig and human skin donors is a developing approach that translates the research to the clinic, including the native microenvironment of the biofilm.
KEY WORDS Bacteria Biofilm Infection Microbiology Swab Wound dressings
MARNIE PETERSON PharmD, PhD, Site Director, Perfectus Biomed Group, Now Part of NAMSA, 3545 South Park Dr., Jackson, Wyoming, 83001, US. 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
SAM WESTGATE PhD, Executive Director, Perfectus Biomed Group, Now Part of NAMSA, Techspace One SciTech Daresbury, Keckwick Lane, Daresbury, Cheshire, WA4 4AB, UK, 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
Raghda Basil Ismael Alkhateeb1, Asmaa Saleem Esmail Ah-Ghurabi2,
Laith Saleh Alkaaby3, Abdulsalam Y. Taha4
1 Department of Cardiac Surgery, Slemani Cardiac Hospital, Sulaymaniyah, Iraq
2 The Diabetes Center in Sulaymaniyah, Sulaymaniyah, Iraq
3 Department of Cardiac Surgery, Iraqi Center for Heart Diseases, Baghdad, Iraq
4 Department of Thoracic and Cardiovascular Surgery, College of Medicine, University of Sulaimani, Sulaymaniyah, Iraq
Email: ansthasia_该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
How to cite this paper: Alkhateeb, R.B.I., Ah-Ghurabi, A.S.E., Alkaaby, L.S. and Taha, A.Y. (2022) Deep Sternal Wound Infections after Coronary Artery Bypass Grafting: Analysis of 29 Cases from Iraq. World Journal of Cardiovascular Surgery, 12, 153-172. https://doi.org/10.4236/wjcs.2022.127012
Received: April 24, 2022
Accepted: July 26, 2022
Published: July 29, 2022
Background: Deep sternal wound infection (DSWI), or mediastinitis, is a devastating complication of coronary artery bypass grafting (CABG). This prospective study aimed to assess our management of DSWI in view of the published literature. Methods: Over 2-years (ending in January 2016), 29 patients (20 males) developed DSWI amongst 520 patients who underwent standard CABG surgeries (5.6%). Pre-, intra- and postoperative variables were documented. Whenever possible, the infections were culture-verified. Besides antibiotics, patients received one or more of the following therapies: drainage, debridement, closed irrigation, sternal re-wiring, vacuum-assisted closure (VAC), and bone resection. Results: the male to female ratio was 2.2:1. Mean age was 58.1 ± 7.3 years. The mean body mass index (BMI) was 27.9 ± 3.4 kg/m2 . There were 18, 16 and 11 patients with diabetes mellitus (DM), hypertension and chronic obstructive pulmonary disease (COPD) respectively. Cardiopulmonary bypass (CPB) was utilized in 26 (89.7%) patients with a mean time of 117.5 ± 23.3 minutes. Most surgeries (n = 21, 72.4%) lasted 5 - 6 hrs. According to Pairolero classification, there were 3 (10.3%) Type I, 22 (75.9%) Type II and 4 (13.8%) Type III infections. Four (13.8%) cases were culture-verified. Twenty-three (79.3%) DSWIs were surgically managed. Sternal re-wiring was performed in 14 (48.3%) cases while VAC was added to other therapies in 2 (6.9%) patients. DSWIs completely resolved in 18 (62.0%) patients within 3 - 24 weeks while two (6.9%) patients died within 30 days. Conclusion: We have identified six independent risk factors for DSWI (male gender, obesity, DM, hypertension, COPD and CPB), five of them are modifiable.
Deep Sternal Wound Infection, Mediastinitis, Coronary Artery Bypass Grafting, Median Sternotomy, Vacuum-Assisted Closure, Wound Debridement
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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