A.Giaccari1 · G. Gliozzo1 · G. Ciccarelli1 · G. Di Giuseppe1 · C. Castellano2 · S. Cum3 · L. Delle Monache4,13 · M. Gallo5 ·M.Lastretti6 · G. Medea7 · M. Monesi8 · R. Napoli9 · B. Pintaudi10 · E. Succurro11 · G. Turchetti
Received: 9 January 2026 / Accepted: 17 March 2026 © The Author(s) 2026
Abstract
Background and aims Although continuous glucose monitoring (CGM) devices are now standard of care among Type 1 diabetes patients, they are still relatively underutilized in Type 2 diabetes (T2D), particularly in those patients not treated with insulin. Widespread adoption continues to be hindered by a combination of factors. Chief among these is the scarcity of long-term, large-scale clinical trials demonstrating the benefits of the use of CGM in T2D. This meta-analysis aimed to address this gap by comparing CGM with self-blood glucose monitoring (SBMG), with primary outcomes of HbA1c and time in range (TIR) in insulin-treated and non-insulin-treated TD2 patients.
Methods and results Following the stringent rules mandated by our National Health Service (which requires a panel com-posed of all stakeholders involved in diabetes treatment, and includes PICO, GRADE, AGREE, and meta-analyses), we performed a systematic review of RCTs that enrolled two groups of individuals with T2D, those treated with insulin (includ-ing basal and basal-bolus regimens), and those receiving treatments other than insulin. All included trials compared CGM with structured blood glucose monitoring (SBGM) with glycated hemoglobin (HbA1c) as the main endpoint. Based on the strength and consistency of the evidence, the panel issued a strong recommendation in favor of CGM for individuals with T2D treated with insulin (including those on basal insulin alone) and for individuals with T2D not treated with insulin, par-ticularly for those with glycated hemoglobin levels≥7%. From a pharmacoeconomic perspective, outcomes were positive in both patient groups.
Conclusion CGM represents a clinically effective and cost-efficient approach to optimizing glycemic control in T2D, becom-ing mandatory among individuals on insulin therapy. Our findings support a shift in clinical practice toward the more widespread use of CGM in T2D, with regulatory frameworks and reimbursement policies needing to adapt accordingly.
Keywords CGM · Type 2 Diabetes · Metanalysis · PICO · GRADE · Guidelines
Communicated by Massimo Federici, M.D.
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1 Center for Endocrine and Metabolic Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS and Università Cattolica del Sacro Cuore, Rome, Italy
2 Azienda USL of Modena, Sassuolo Hospital, Sassuolo, Italy
3 Diabetes and Diabetic Foot Care Unit, ASUGI, Monfalcone, Italy
4 National Board Member of FAND (Italian Association for the Rights of Diabetic People), Roma, Italy
5 Department of Endocrinology and Metabolic Diseases, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
6 Order of Psychologists of Lazio, Rome, Italy
7 Italian Society of General Medicine (SIMG), Florence, Italy
8 Territorial Diabetology Unit, AUSL Ferrara, Ferrara, Italy
9 Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
10 Diabetes Unit, Niguarda Cà Granda Hospital, Milan, Italy
11 Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
12 Institute of Management, Scuola Superiore Sant’Anna, Pisa, Italy
13 Patient Advocacy Lab, ALTEMS – Università Cattolica del Sacro Cuore, Rome, Italy
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引用本文:简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.
通信作者:邓呈亮,Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
A case series was conducted to demonstrate the safe and effective use of a 14-day Single Use Negative Pressure Wound Therapy System (sNPWT) in the management of static, ‘hard-to-heal’ wounds. When used in conjunction with optimal wound care strategies, including holistic assessment and comprehensive patient empowerment and education, the use of sNPWT resulted in the closure of all chronic wounds in this case series despite complex histories. This case series demonstrates enhanced results when a proactive, holistic and patient-centred approach is adopted in conjunction with sNPWT.
Authors:
Hayley Ryan and Joanne Handsaker
Hayley Ryan is Director of Wounds Rescue/Wounds Australia Board Director & Chair, Wound Clinical Nurse Consultant (WCNC);
Joanne Handsaker is Clinical Strategy –Global Clinical Strategy Specialist, Smith and Nephew
Practitioners have advocated for new ways of working, such as shared wound care, to address the challenges in chronic wound management. Shared wound care practiced alongside the use of long-wear advanced foam dressings has the potential to optimise community wound care*; releasing time for nurses and healthcare systems, and empowering patients. Many practitioners already use elements of shared wound caren with patients but require support to implement the approaches more formally and reduce practice variation. This article will discuss shared wound care from an individual practitioner’s perspective, addressing how shared wound care is beneficial, accessible, clinically effective, scalable, and implementable, and facilitate discussions about standardising implementation within their health system.
*Wear time of up to 5 to 7 days (Simon and Bielby, 2014; Joy et al, 2015; Smith+Nephew, 2016b; 2016a)
Amanda Loney, Certified Nurse Specialised, Wound, Ostomy and Continence (WOCC(C)), Bayshore Home Care Solutions Hamilton, Ontario, Canada;
Catherine Milne, Advanced Practice WOC Nurse in Bristol, Connecticut, Clinical Instructor Yale School of Nursing, Connecticut, United States
Aldo Conti, Massimiliano Brilli, Edgardo Norgini, Stefano Falini, Laura De Fina, Genni Spargi and Stefano Gasperini
Stagnant wounds are wounds that don’t progress in the healing process,despite adequate therapy. Blue light photobiomodulation is a novel therapy that has been demonstrated to positively influence wound healing by stimulating the resolution of the inflammatory response and promoting tissue repair. This case series evaluated the effect of photobiomodulation on five patients with silent wounds of various aetiologies who were treated with blue light for four weeks. At the end of the observation period, five patients had a significant reduction in lesion area, an improvement in wound bed score and a reduction in pain.
Aldo Conti is a Wound Care Nurse Expert, Wound Care Outpatient Clinic, Hyperbaric Medicine Service, UOC Anaesthesia and Reanimation;
Massimiliano Brilli is a Wound Care Nurse Expert, Wound Care Outpatient Clinic, Hyperbaric Medicine Service, UOC Anaesthesia and Reanimation;
Edgardo Norgini is a Wound Care Nurse Expert, Wound Care Outpatient Clinic, Hyperbaric Medicine Service, UOC Anaesthesia and Reanimation;
Stefano Falini is Head of Hyperbaric Medicine Service, UOC Anaesthesia and Reanimation;
Laura De Fina, Hyperbaric Medicine Service, UOC Anaesthesia and Reanimation;
Genni Spargi is Director UOC Anaesthesia and Reanimation; all at Misericordia Hospital, Grosseto, Italy;
Stefano Gasperini is a Medical Advisor, Pisa, Italy
朱由瑾,杨晓静,冯冬梅(河北北方学院附属第一医院皮肤科河北张家口075000)
基金项目:张家口市科学技术研究与发展计划(项目名称:激光联合皮下分离术治疗瘢痕的临床研究:项目编号:18l1032D一4)
[摘要]目的:评价重组人表皮生长因子在面部软组织损伤美容修复中的应用价值。方法:按照随机数字法将2016年1月一2018年1月笔者医院收治的100例面部软组织损伤患者分为对照组与研究组,每组50例。对照组采用美容整形外科手术进行修复,研究组在对照组基础上加用重组人表皮生长因子凝胶。比较两组患者修复效果、住院时间、损伤愈合时间及术后并发症发生情况。
结果:研究组修复效果明显高于对照组,研究组的损伤愈合时间明显短于对照组,两组比较差异有统计学意义(P<0.05);两组患者住院时间比较,差异无统计学意义;研究组术后并发症发生率为8。00%,明显低于对照组的24.00%,差异有统计学意义(P<O.05)。结论:重组人表皮生长因子能促进面部软组织的损伤修复,提高美容修复效果,降低术后并发症。
[关键词]面部软组织损伤;美容修复;重组人表皮生长因子;凝胶;整形外科手术
[中图分类号]R751.05
[文献标志码]A
[文章编号]1008—6455(2019)一01-0061-03
Application of Recombinant Human Epidermal G的wth Factor in the Cosmetic
Repair of Facial Soft Tissue Injury
ZHU You_jjn,YANG Xiao_jing,FENG Dong—mei
(Department of Dermatology, the First Affiliated Hospital of Hebei North University. zhangjiakou 075000,Hebei,China)
Abstracts: Objective To evaluate the value of recombinant human epidermal growth factor in the cosmetic repair of patients with facial soft tissue injury.
Methods 100 patients with facial soft tissue injury which was divided into control group and observation group according to random number table in our hospital from January 2016 to January 2018, 50 cases in each group. The patients were repaired by aesthetic plastic surgery in control group and the patients were added recombinant human epidermal growth factor gel based on the aesthetic plastic surgery in research group. The good rate, hospital stay, injury healing time and postoperative complication was compared between two groups.
Results The good rate of observation group was significantly higher than that of control group, the injury healing time of observation group was significantly shorter than that of control group(P < <0.05), there was no statistical significance on hospital staybetween two groups, the occurrence rate of postoperative complication in observation group(8.00%) was significantly lower than that of control group(24.00%,P<0.05). Conclusion Recombinant human epidermal growth factor could promote the repair of facial soft tissue injury, improve the effect of cosmetic repair and reduce postoperative complication.
Key words: facial soft tissue injury; esthetics repair; recombinant human epidermal growth factor; gel; plastic surgery
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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