A.Giaccari1 · G. Gliozzo1 · G. Ciccarelli1 · G. Di Giuseppe1 · C. Castellano2 · S. Cum3 · L. Delle Monache4,13 · M. Gallo5 ·M.Lastretti6 · G. Medea7 · M. Monesi8 · R. Napoli9 · B. Pintaudi10 · E. Succurro11 · G. Turchetti
Received: 9 January 2026 / Accepted: 17 March 2026 © The Author(s) 2026
Abstract
Background and aims Although continuous glucose monitoring (CGM) devices are now standard of care among Type 1 diabetes patients, they are still relatively underutilized in Type 2 diabetes (T2D), particularly in those patients not treated with insulin. Widespread adoption continues to be hindered by a combination of factors. Chief among these is the scarcity of long-term, large-scale clinical trials demonstrating the benefits of the use of CGM in T2D. This meta-analysis aimed to address this gap by comparing CGM with self-blood glucose monitoring (SBMG), with primary outcomes of HbA1c and time in range (TIR) in insulin-treated and non-insulin-treated TD2 patients.
Methods and results Following the stringent rules mandated by our National Health Service (which requires a panel com-posed of all stakeholders involved in diabetes treatment, and includes PICO, GRADE, AGREE, and meta-analyses), we performed a systematic review of RCTs that enrolled two groups of individuals with T2D, those treated with insulin (includ-ing basal and basal-bolus regimens), and those receiving treatments other than insulin. All included trials compared CGM with structured blood glucose monitoring (SBGM) with glycated hemoglobin (HbA1c) as the main endpoint. Based on the strength and consistency of the evidence, the panel issued a strong recommendation in favor of CGM for individuals with T2D treated with insulin (including those on basal insulin alone) and for individuals with T2D not treated with insulin, par-ticularly for those with glycated hemoglobin levels≥7%. From a pharmacoeconomic perspective, outcomes were positive in both patient groups.
Conclusion CGM represents a clinically effective and cost-efficient approach to optimizing glycemic control in T2D, becom-ing mandatory among individuals on insulin therapy. Our findings support a shift in clinical practice toward the more widespread use of CGM in T2D, with regulatory frameworks and reimbursement policies needing to adapt accordingly.
Keywords CGM · Type 2 Diabetes · Metanalysis · PICO · GRADE · Guidelines
Communicated by Massimo Federici, M.D.
A. Giaccari 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
1 Center for Endocrine and Metabolic Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS and Università Cattolica del Sacro Cuore, Rome, Italy
2 Azienda USL of Modena, Sassuolo Hospital, Sassuolo, Italy
3 Diabetes and Diabetic Foot Care Unit, ASUGI, Monfalcone, Italy
4 National Board Member of FAND (Italian Association for the Rights of Diabetic People), Roma, Italy
5 Department of Endocrinology and Metabolic Diseases, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
6 Order of Psychologists of Lazio, Rome, Italy
7 Italian Society of General Medicine (SIMG), Florence, Italy
8 Territorial Diabetology Unit, AUSL Ferrara, Ferrara, Italy
9 Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
10 Diabetes Unit, Niguarda Cà Granda Hospital, Milan, Italy
11 Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
12 Institute of Management, Scuola Superiore Sant’Anna, Pisa, Italy
13 Patient Advocacy Lab, ALTEMS – Università Cattolica del Sacro Cuore, Rome, Italy
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引用本文:简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.
通信作者:邓呈亮,Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
EXPERT PANEL
Luxmi Dhoonmoon (Co-chair), Tissue Viability Nurse Consultant, Central and North West London NHS Foundation Trust
Harikrishna K.R. Nair (Co-chair), Head and Consultant of Wound Care Unit, Department of Internal Medicine, Kuala Lumpur Hospital, Malaysia; Professor, Faculty of Medicine, Lincoln University Malaysia; Professor, Institute of Health Management; Austria, Adjunct Professor, Department of Surgery, Institute of Medical Sciences, Banares Hindu University, India; Executive Director, College of Wound Care Specialists
Zulfiqarali Abbas, Endocrinologist, Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam; Abbas Medical Centre, Dar es Salaam, Tanzania
Ethel Andrews, Wound Specialist, Life Brenthurst Hospital/Netcare Mulbarton Hospital, Johannesburg, South Africa; Visiting Lecturer, University of Witwatersrand; Past President, South African Burn Society; International Burns Society Nurse Award recipient 2022
Simone McConnie, Diabetic Footcare Specialist Podiatrist, Comfeet Foot Care Clinic, Barbados
Jennifer Pearson, Head of Nursing Royal Orthopaedic Hospital Birmingham; BAME Nurse of the Year 2022; Regional Lead Chief Nursing Officer (England), Black Minority Ethnic Strategic Advisory Group
Mohamed Waheed, Plastic Surgeon, Head of the Department of Surgery, Indira Gandhi Memorial Hospital, Maldives
Mandika Wijeyaratne, Head of the Department of Surgery, Faculty of Medicine, University of Colombo, Sri Lanka
PUBLISHED BY:
Wounds International 108 Cannon Street London EC4N 6EU, UK
Tel: + 44 (0)20 7627 1510 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 www.woundsinternational.com © Wounds International, 2023
FOREWORD
While patient populations vary across the world, evidence shows that in many areas there are discrepancies in wound care due to variations in skin tone; for example, patients with dark skin are more likely to be diagnosed with higher-category pressure ulcers (PUs) (Oozageer Gunowa et al, 2017). This is due to a lack of accurate assessment and early identification; for example, the initial "redness" seen on light skin may not be present in dark skin and thus be missed in the initial assessment. The majority of existing evidence around skin tones in wound care is in the field of PUs, with a lack of evidence identified in other conditions and wound types (Oozageer Gunowa, 2022).
A literature search published in 2022 (Oozageer Gunowa, 2022) highlighted gaps in the evidence around skin tones and the need for further research in this area of patient care. Further, in wound care education, there is a need for the inclusion of dark skin tones in casestudies and photographs as well as to address the gap in bias around light skin tones and lack of understanding of how to assess different skin tones (Dhoonmoon et al, 2021).
Skin changes in people with dark skin tones are not observed quickly enough on a global scale. ‘Global Majority’ is a collective term for people who are Black, Asian, Brown, dual-heritage, indigenous to the global south, and or have been racialised as 'ethnic minorities'; globally, these groups currently represent approximately 80% of the world's population (Campbell-Stephens, 2020).
To address these gaps, a group of global experts convened for an online meeting in September 2022 to develop this international consensus document, focusing on inclusive language, assessment, and treatment of all skin tones, to improve patient outcomes. The members of the expert group work in different areas of the world, with differing patient groups and within different healthcare systems; the aim of this meeting and the resulting document was to learn from shared experiences and provide guidance on best practice to improve outcomes for all patients, with a differing range of skin tones.
This international consensus document aims to:
▆ Provide practical guidance on accurate assessment and diagnosis in all skin tones
▆ Provide guidance on language and descriptors to use, aiding clear patient communication
▆ Discuss different geographical and cultural considerations across the globe
▆ Dispel myths relating to skin tones
▆ Focus on the future, the need for education and how outcomes can continue to improve.
The overall aim is to improve clinician confidence in delivering best practice to all patients, with the ultimate aim of improving patient experiences and outcomes.
Luxmi Dhoonmoon (Co-chair)
Harikrishna K. R. Nair (Co-chair)
Patient assessment is the foundation of all care. Effective treatment cannot be commenced without
accurate and thorough patient-centred assessment. Assessment may also mean that key preventative
measures can be put in place that reduce a patient’s risk of requiring further care.
A thorough inspection of the skin should be performed, as well as a baseline knowledge of identifying
and taking into account the patient's baseline skin tone so that any changes to the patient's skin
can be monitored and identified early (Dhoonmoon et al, 2021). A lack of early identification of skin
changes can mean that important signs are missed, which can lead to further and preventable skin
and tissue breakdown and damage.
A holistic wound assessment considers the entire patient, including their health, environment,
physical, psychological and psychosocial factors, as well as their skin tone. Although not well
documented, different skin tones respond differently to injury, pressure, healing and treatment.
Therefore, it is critical that the assessment and any subsequent care are tailored to the individual
patient and their needs from the beginning.
A holistic assessment should include:
▆ The patient’s skin including their skin tone
▆ Their overall health
▆ Their medical history
▆ Their wound or skin condition
▆ Their lifestyle and environment
▆ Their individual needs and preferences
▆ Their education and ability to follow information and guidance, especially when caring for a wound at home
▆ Their socioeconomic status, as treating skin conditions in a private hospital setting can be expensive, and treatments may take longer to work depending on skin type and vascular status.
Author: Theophila Lan Si’Ai
Theophila Lan Si’Ai is Senior Podiatrist, Singapore General Hospital, Singapore
Complex and complicated wounds (CCWs) tend to exhibit slow wound healing and poor prognoses despite good standards of care. Numerous literature demonstrated the efficacy of TLC-NOSF dressing (UrgoStart®) in healing of both acute and chronic wounds. The author thus hypothesised that inclusion of TLCNOSF dressing in dressing regimes would enhance wound healing and improve outcomes in CCW. This paper successfully verifies the hypothesis on three such wounds, with good wound healing outcomes achieved.
Author:
Corey Heerschap
Corey Heerschap is Wound/ Ostomy Clinical Nurse Specialist at Royal Victoria Regional Health Centre in Barrie, ON, Canada, and a PhD student at Queens University in Kingston, ON, Canada. He is the President-Elect of Nurses Specialized in Wound, Ostomy and Continence Canada, Inaugural Panel Member of the Canadian Pressure Injury Advisory Panel, and Education CoLead for the Commonwealth Wound Care Resource Alliance.
Joyce Black
Joyce Black is Professor, College of Nursing, University of Nebraska Medical Center, Omaha, Nebraska, US
Despite the frequency of pressure ulcers on the heels, little is written about them. While these ten top tips will not fill the literature gap, it may help you with this common problem.
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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