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星期二, 19 11月 2019

魏爱周

毕业于山东大学医学院临床医学（六年制）系，2011年获山东大学骨外科（显微外科方向）专业硕士学位，攻读硕士学位期间，共参加3届全国显微解剖与临床高级研修班，在山东省立医院手足外科实习工作2年，2011年至今工作于郑州大学第一附属医院烧伤修复重建科，致力于大面积烧伤及各种特殊烧伤的救治、电击伤、褥疮以及各种难愈性创面的治疗、糖尿病足系统性治疗、断指再植、手足功能重建、手指再造、各种皮瓣修复复杂创面、周围神经损伤修复。对于皮肤色素痣、皮肤肿瘤、皮肤癌、瘢痕癌等治疗有丰富的经验。

星期二, 19 11月 2019

EMPIRICAL STUDIES Endogenous Thymosin Beta-4 Expression in Sacrococcygeal Pilonidal Sinus Disease: A Retrospective, Immunohistochemical Analysis of Excisional Skin Biopsy Samples

Authors

Sevinc Sahin

Keywords

pilonidal sinus

星期二, 19 11月 2019

EMPIRICAL STUDIES The International Consolidated Venous Ulcer Guideline Update 2015: Process Improvement, Evidence Analysis, and Future Goals

Authors

Kara S. Couch

CWS; Lisa Corbett

CWOCN; Lisa Gould

星期二, 19 11月 2019

EMPIRICAL STUDIES A Descriptive Study to Explore the Effect of Peristomal Skin Complications on Quality of Life of Adults With a Permanent Ostomy

Authors

Diane Maydick-Youngberg

Keywords

星期二, 19 11月 2019

EMPIRICAL STUDIES A Retrospective Study of the Impact of Pressure Ulcers on Survival in Elderly Persons With Chronic Diseases

Authors

Efraim Jaul

Joshua P. Rosenzweig

Keywords

pressure ulcers

星期二, 19 11月 2019

EMPIRICAL STUDIES Cross-cultural Adaptation and Validation of the Stoma Quality of Life Questionnaire for Patients With a Colostomy or Ileostomy in Brazil: A Cross-sectional Study

Authors

Ana L√≠via de Oliveira

Larissa Loures Mendes

Michele Pereira Netto

K2 Content

干细胞在整形修复美容领域研究和临床试验的专家共识 2024-11-07 00:00

中国医师协会整形美容医师分会干细胞和再生医学学组
【摘要】干细胞是一类具有分化潜能的细胞,随着近年来对干细胞研究的深人,干细胞在促进组织修复与再生的作用也得到越来越多的关注。本学组就干细胞在整形修复美容领域的基础研究及临床试验研究组织专家讨论,并将专家共识总结成文,为干细胞在整形修复美容领域的研究与未来临床转化提供参考与支持。
An Innovative Treatment Using Calcium Hydroxyapatite for Non-Surgical Facial Rejuvenation: The Vectorial-Lift Technique 2024-11-06 00:00

Virginia Marcia Amaral1 iD• Helena Hotz Arroyo Ramos2 • Fernanda Aquino Cavallieri3 • Mariana Muniz4 • Guilherme Muzy5 • Ada Trindade de Almeida6

1 IVA Medical Institute, Av. dos Bandeirantes 1518, Belo Horizonte CEP: 30.315-032, Brazil

2 Vito´ria, Brazil

3 Rio de Janeiro, Brazil

4 Sa˜o Paulo, Brazil

5 Sa˜o Paulo, Brazil

6 Hospital do Servidor Pu´blico Municipal de Sa˜o Paulo, Sa˜o Paulo, Brazil

Received: 13 January 2024 / Accepted: 9 April 2024 / Published online: 7 May 2024

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© The Authors 2024, corrected publication 2024

Abstract Background The facial aging process entails alterations in the volume, shape, and texture of all skin layers over time. Calcium hydroxyapatite (CaHA) is a well-established safe skin filler with unique properties to resolve some skin alterations by stimulating neocollagenesis. The vectoral-lift (V-lift) technique targets the global repositioning of facial structures by addressing distinct anatomical injection planes. It includes deep facial augmentation with Radiesse PlusTM to retain ligament restructuring and superficial subcutaneous enhancement with diluted Radiesse DuoTM. Herein, we present cases that illustrate the use of this approach.

Methods This pilot study enrolled 36 participants (33 women and three men; ages 37–68 years) in a Brazilian clinical setting, and all patients underwent a single treatment. Photographs were taken at rest, in frontal and oblique views, before injection, and 90 days after treatment.

Results Treatment resulted in elevation of the upper and middle face, notable improvements in the infraorbital hollow, and adjustment of the mean facial volume.

Conclusions The V-lift technique is a three-dimensional pan-facial treatment that relies on ligament support and face vectoring to obtain a lifting effect and facial contour restoration. It encompasses deep facial augmentation involving the use of Radiesse PlusTM for restructuring and retaining ligaments and Radiesse DuoTM for superficial subcutaneous enhancement. This approach targets a global repositioning of the facial structures by addressing distinct anatomical injection planes. It achieves a repositioning of the overall facial anatomy without requiring a substantial volumetric expansion.

Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Keywords Skin aging Collagen Plastic surgery Dermatology Aesthetics Calcium hydroxyapatite Biostimulation
The efcacy of hyaluronic acid fragments with amino acid in combating facial skin aging: an ultrasound and histological study 2024-11-05 00:00

Antonio Scarano1 · E. Qorri2 · A. Sbarbati3 · S. A. Gehrke4 · Alessio Frisone1 · D. Amuso3 · Sergio Rexhep Tari1

Received: 30 March 2024 / Accepted: 17 May 2024 / Published online: 24 June 2024

© The Author(s) 2024

Antonio Scarano

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E. Qorri

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A. Sbarbati

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S. A. Gehrke

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D. Amuso

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Sergio Rexhep Tari

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1 Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Strada Marcello Mucci 38/B, 66100 Chieti, Italy

2 Department of Dentistry, Faculty of Medical Sciences, Albanian University, 1001 Tirana, Albania

3 Department of Neurosciences, Biomedicine and Movement Sciences, Anatomy and Histology Section, School of Medicine, University of Verona, Verona, Italy

4 Department of Research, Bioface/PgO/UCAM, Montevideo, Uruguay

Abstract

Background Various techniques have been employed in aesthetic medicine to combat skin aging, in particular that of the facial region. Hyaluronic acid is utilized to enhance moisture levels and extracellular matrix molecules. This study aims to histologically assess the efects of low molecular weight hyaluronic acid fragments combined with amino acids (HAAM) on facial skin rejuvenation through intradermal microinjections.

Methods A total of twenty women, with an average age of 45 and ranging from 35 to 64 years old, participated in the study, including 8 in menopause and 12 in the childbearing age group. Mesotherapy was used to administer HAAM to the patients. Prior to and three months after the treatment, each patient underwent small circular punch biopsies. Ultrasound examinations were conducted using B-mode, capturing 2D images in longitudinal or transverse orientations with frequencies ranging from 5 to 13 Mega-hertz (MY LAB X8, ESAOTE, Genova, Italy). A total of 60 ultrasound examinations were taken, with 30 collected before treatment and 30 after treatment.

Results The histological analysis demonstrates an increase in fbroblast activity resulting in the production of Type III reticular collagen, as well as an increased number of blood vessels and epidermal thickness. However, the analysis of ultrasound data before and after treatment showed no statistical diference in skin thickness in malar area, chin and mandibular angle.

Conclusions Histological assessments indicate that subcutaneous infltration of HAAM has a substantial impact on the dermis of facial skin.

Keywords Hyaluronic acid · Hyaluronic acid fragments · Amino acid · Fibroblast · Skin aging · Ultrasound

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主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

伤口世界

魏爱周

EMPIRICAL STUDIES Endogenous Thymosin Beta-4 Expression in Sacrococcygeal Pilonidal Sinus Disease: A Retrospective, Immunohistochemical Analysis of Excisional Skin Biopsy Samples

EMPIRICAL STUDIES The International Consolidated Venous Ulcer Guideline Update 2015: Process Improvement, Evidence Analysis, and Future Goals

EMPIRICAL STUDIES A Descriptive Study to Explore the Effect of Peristomal Skin Complications on Quality of Life of Adults With a Permanent Ostomy

EMPIRICAL STUDIES A Retrospective Study of the Impact of Pressure Ulcers on Survival in Elderly Persons With Chronic Diseases

EMPIRICAL STUDIES Cross-cultural Adaptation and Validation of the Stoma Quality of Life Questionnaire for Patients With a Colostomy or Ileostomy in Brazil: A Cross-sectional Study

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Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

伤口世界

魏爱周

EMPIRICAL STUDIES Endogenous Thymosin Beta-4 Expression in Sacrococcygeal Pilonidal Sinus Disease: A Retrospective, Immunohistochemical Analysis of Excisional Skin Biopsy Samples

EMPIRICAL STUDIES The International Consolidated Venous Ulcer Guideline Update 2015: Process Improvement, Evidence Analysis, and Future Goals

EMPIRICAL STUDIES A Descriptive Study to Explore the Effect of Peristomal Skin Complications on Quality of Life of Adults With a Permanent Ostomy

EMPIRICAL STUDIES A Retrospective Study of the Impact of Pressure Ulcers on Survival in Elderly Persons With Chronic Diseases

EMPIRICAL STUDIES Cross-cultural Adaptation and Validation of the Stoma Quality of Life Questionnaire for Patients With a Colostomy or Ileostomy in Brazil: A Cross-sectional Study

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