Maja Paterska 1 , Bogusław Czerny 2,3 and Judyta Cielecka-Piontek 4,*

1 Department of Pharmacology and Phytochemistry, Institute of Natural Fibres and Medicinal Plants, Wojska Polskiego 71b, 60-630 Poznan, Poland; 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

2 Department of Stem Cells and Regenerative Medicine, Institute of Natural Fibres and Medicinal Plants, 62-064 Plewiska, Poland; 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

3 Department of General Pharmacology and Pharmacoeconomics, Pomeranian Medical University in Szczecin, 71-210 Szczecin, Poland

4 Department of Pharmacognosy and Biomaterials, Faculty of Pharmacy, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland

* Correspondence: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

Citation: Paterska, M.; Czerny, B.;

Cielecka-Piontek, J. Macrofungal

Extracts as a Source of Bioactive

Compounds for Cosmetical

Anti-Aging Therapy: A

Comprehensive Review. Nutrients

2024, 16, 2810. https://doi.org/

10.3390/nu16162810

Academic Editors: Arrigo Cicero and

Akiko Kojima-Yuasa

Received: 26 June 2024

Revised: 21 August 2024

Accepted: 22 August 2024

Published: 22 August 2024

Abstract: For centuries, mushrooms have been used as a component of skincare formulations. Environmental stresses and a modern lifestyle expose the skin to accelerated aging. To slow down this process, natural anti-aging skincare ingredients are being sought. In this review, 52 scientific publications about the effects of chemical compounds extracted from the fruiting bodies of macrofungi on skin cells were selected. The effects of extracts from nine species that are tested for anti-aging effects have been described. According to available literature data, macrofungi contain many polysaccharides, phenolic compounds, polysaccharide peptides, free amino acids, sterols, proteins, glycosides, triterpenes, alkaloids, which can have an anti-aging effect on the skin by acting as antioxidants, photoprotective, skin whitening, moisturizing, anti-inflammatory and stabilizing collagen, elastin and hyaluronic acid levels in the skin.

Keywords: anti-aging; Trametes versicolor; Schizophyllum commune; Tremella fuciformis; Pleurotus ostreatus; Agaricus subrufescens; Volvariella volvacea; Ganoderma lucidum; Letinula edodes; Inonotus obliquus; mushrooms; macrofungi