刘军，曾志男，梁晓燕，冷雨欣，李儒新

（中国科学院上海光学精密机械研究所，上海 201800）

摘要：超快超强激光兼具超快时域特性和超高峰值功率特性，为人类在实验室中创造出了前所未有的超快时间、超高强场、超高温度和超高压力等极端物理条件，成为用于拓展人类认知的前沿基础科学研究最重要的工具之一。本文从超快激光和超强激光的应用与发展需求出发，系统调研了国内外研究和科学应用的现状，提出了我国超快激光和超强激光的发展思路与目标以及为实现这些目标需要重点发展的相关方法和技术。针对超高峰值功率和高重复频率超强激光面向未来的重要方向，分析了我国分阶段发展的重点内容，突出了相关技术与配套元器件研究的重要性。此外，在注重基础研究、多方面吸引和培育人才、加强国际合作、促进产业化等方面提出了超快超强激光发展的措施建议，以期为我国激光技术与科学应用的稳步发展提供方向参照。

关键词：超快超强激光；飞秒激光；阿秒激光；拍瓦激光；发展趋势

中图分类号：O437 文献标识码：A

Development Trend of Ultrafast and Ultraintense

Lasers and Their Scientific Application

Liu Jun, Zeng Zhinan, Liang Xiaoyan, Leng Yuxin, Li Ruxin

(Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China)

Abstract: Ultrafast and ultraintense lasers have ultrafast temporal and ultraintense focal intensity properties. They can create unprecedentedly extreme experimental conditions with ultrahigh time resolution, temperature, and pressure as well as ultrahigh-strength field. The ultrafast and ultraintense laser is one of the important tools for frontier fundamental research meant for extending the knowledge of mankind. This paper starts with the analysis of the application and development demands of the ultrafast and ultraintense lasers and then systematically investigates the research status of these lasers in China and abroad. Based on this, the developing routes and targets of ultrafast and ultraintense lasers as well as the related technologies needed for achieving these targets are proposed. Particularly, we proposed the respective key steps for developing ultraintense lasers with ultrahigh peak power and those with high repetition frequency, and emphasized the study of related technologies and ancillary components. Furthermore, several suggestions are proposed for the development of ultrafast and ultraintense lasers in China, including strengthening fundamental researches, improving personnel training, enhancing international cooperation, and promoting market application, hoping to provide references for the steady development of China’s laser technologies.

Keywords: ultraintense and ultrashort laser; femtosecond laser; attosecond laser; petawatt laser; development trend

贺 潇1 ，晁生武2＊

1 青海大学研究生院，青海 西宁

2 青海大学附属医院烧伤整形科，青海 西宁

收稿日期：2022年6月19日；录用日期：2022年7月11日；发布日期：2022年7月21日

摘 要

近年来，由于人口老龄化的加剧，慢性创面患者数量不断增多。因其发病机制尚未研究清楚，治疗较困难，治疗方式多样化，无固定模式，应用许多药物的治疗效果不佳。本文以“TIME”原则为基点，将慢性创面创面床准备的研究进展予以综述，旨在为慢性创面的诊治提供新思路。

关键词

慢性创面，创面床，“TIME”原则，创面愈合

Application Progress of the TIME Principle of Wound Bed Preparation in Chronic Wounds

Xiao He1, Shengwu Chao2*

1 Graduate School of Qinghai University, Xining Qinghai

2 Department of Burns and Plastic Surgery, Affiliated Hospital of Qinghai University, Xining Qinghai

Received: Jun. 19th, 2022; accepted: Jul. 11th, 2022; published: Jul. 21st, 2022

Abstract

In recent years, due to the aggravation of population aging, the number of chronic wound patients has continued to increase. Because the pathogenesis has not been clearly studied, the treatment is difficult, the treatment methods are diversified, and there is no fixed pattern. The treatment effect of many drugs is not good. Based on the “TIME” principle, this paper reviews the research progress of wound bed preparation for chronic wounds, aiming to provide new ideas for the diagnosis and treatment of chronic wounds.

Keywords

Chronic Wounds, Wound Bed, TIME Principle, Wound Healing

Rumana Alim1*, Sofia Andalib Safiullah1, Shaila Munwar1, Ishad Mazhar1, Sifat Uz Zaman2, MD. Sarwar Bari3

1 Department of Microbiology, Medical College for Women and Hospital, Dhaka, Bangladesh

2 Infection Prevention and Control Division, Medlife Healthcare Limited, Dhaka, Bangladesh

3 Department of Printing & Publications, Dhaka, Bangladesh

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How to cite this paper: Alim, R., Safiullah, S.A., Munwar, S., Mazhar, I., Zaman, S.U. and Bari, M.S. (2022) Wound Infection Caused by Chromobacterium violaceum: A Case Report from a Tertiary Care Hospital in Bangladesh. Advances in Microbiology, 12, 83-89.

Received: January 17, 2022

Accepted: February 21, 2022

Published: February 24, 2022

Copyright © 2022 by author(s) and Scientific Research Publishing Inc.

This work is licensed under the Creative Commons Attribution International License (CC BY 4.0).

http://creativecommons.org/licenses/by/4.0/

https://doi.org/10.4236/aim.2022.122007

Abstract

      Chromobacterium violaceum is a Gram negative, facultative anaerobe, generally present in water, soil in tropical and subtropical regions. This bacterium is an emerging environmental pathogen that causes life threatening infection in humans and animals. It can cause wound infection, visceral abscess, septicaemia, meningitis, diarrhoea, UTI. It is associated with significant mortality due to severe systemic infection. As the bacteria have high spreading tendency leading to sepsis, early identification and prompt treatment is necessary. Here we report a case of Chromobacterium violaceum wound infection in a 9 years old male from Dhaka, who was successfully treated with combination of cefixime and flucloxacillin antibiotics as per culture sensitivity report.

Keywords

Chromobacterium violaceum, Wound Infection, Antibiotics

      A mobile application for wound care (Minuteful) was trailed over a seven-month period in an acute inpatient setting in Northwest England. During the trial an increase in the availability of wound photography was noted (+37%), a reduction in inappropriate tissue viability nurse reviews (-10%) and the identification of mis-reported pressure ulcers (n=65). Challenges noted during the implementation included initial software compatibility issues with the tablets available on the wards and poor staff engagement. Overall, this initial trial indicates the potential safety, economic and service efficiency improvements that may be possible via implementation of mobile application technology in wound care. Further robust studies are needed to explore the initial findings of this trial in greater depth.

KEY WORDS： Acute care   Chronic wounds   Mobile application   Wound care

MATTHEW WYNN

Honorary Tissue Viability Nurse- Northern Care Alliance NHS Foundation Trust' LUCY SCHOLES Senior Tissue Viability Nurse, Northern Care Alliance NHS Foundation Trust 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。