Bronte Jeffrey1,2*, Logan Gardner6,7, Michelle Le1 , Julie Frost1 and Ming Wei Lin1,3,4,5
*Correspondence: Bronte Jeffrey 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
1 Department of Clinical Immunology, Westmead Hospital, Sydney, Australia
2 St Vincent’s Clinical School, University of New South Wales, Sydney, Australia
3 Faculty of Medicine and Health, University of Sydney, Sydney, Australia
4 Department of Immunopathology, Westmead Hospital, Sydney, Australia
5 Centre for Immunology and Allergy Research, Westmead Institute of Medical Research, Sydney, Australia
6 Allergy, Asthma and Clinical Immunology, The Alfred Hospital, Melbourne, Australia
7 School of Public Health & Preventive Medicine, Monash University, Melbourne, Australia
© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
İbrahim Halil Aydoğdu | Esen Özkaya Department of Dermatology and Venereology, İstanbul Faculty of Medicine, İstanbul University, İstanbul, Turkey
Correspondence: İbrahim Halil Aydoğdu (该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。)
Received: 26 April 2025 | Revised: 14 June 2025 | Accepted: 30 June 2025
Funding: The authors received no specific funding for this work.
Keywords: allergic contact dermatitis | carbamate | epidemiology | glove | mercapto | nonoccupational | occupational | patch test | rubber additives | thiuram
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2025 The Author(s). Contact Dermatitis published by John Wiley & Sons Ltd.
ABSTRACT
Background: Rubber additives are common causes of allergic contact dermatitis (ACD) worldwide, yet data from Turkey remain
Objectives: To evaluate the prevalence of rubber additive sensitisation and its clinical/occupational relevance in a tertiary re ferral centre.
Methods: A retrospective study on 2687 consecutively patch-tested patients with rubber additives at our allergy unit between 1996 and 2023.
Results: Rubber sensitisation was found in 10.6%, with a slight increase after 2010. Male predominance was noted (female: male=1:2.3). Thiurams and carbamates were the most frequent sensitizers. ACD was diagnosed in 7.9%, primarily caused by gloves (85.5%). Hands were most commonly affected (94.4%). Logistic regression analysis showed that thiuram and carba mate sensitisation was significantly associated with hand eczema, while benzothiazole derivatives were linked to foot eczema. Airborne ACD occurred in 4.2%, mainly in healthcare workers. Hand eczema with and without wrist extension was observed with similar frequency. Occupational ACD accounted for 79.3% of cases, especially among construction (56.8%) and healthcare workers (14.8%), with a relative increase in the latter group after 2015.
Conclusions: The high prevalence of sensitisation from rubber gloves is concerning. Legal measures are urgently needed, includ ing safer additives and clearer glove labelling. Patch testing remains essential, even without the classic glove-pattern distribution.
原创:伤口治疗及造口护理中心
足部是糖尿病这个多系统疾病的一个复杂的靶器官。糖尿病患者因周围神经病变与外周血管疾病合并过高的机械压力,可引起足部软组织及骨关节系统的破坏与畸形形成,进而引发一系列足部问题,从轻度的神经症状到严重的溃疡、感染、血管疾病、Charcot关节病和神经病变性骨折。如果积极治疗不能充分解决下肢出现的症状和并发症,则会造成灾难性的后果。因此,在糖尿病患者中开展对足部问题的早期预防和治疗将有重要的意义。
随着现在人们生活水平的逐渐提高,有一种“富贵病”在生活中逐渐出现,渐渐地已经成为生活中的常见病,它就是我们常说的糖尿病。而今天小编不给大家讲糖尿病的相关知识,而是讲一种因糖尿病而引起的一种并发症,它的名字叫糖尿病足!
下肢静脉溃疡
下肢静脉性溃疡,俗称“老烂腿”,是下肢静脉疾病的常见临床表现。下肢静脉性溃疡常常反复发作,溃疡久治不愈,严重影响患者的正常生活,因此一旦出现下肢静脉性溃疡的现象,患者应该及时到正规医院的血管外科就医,以查清病因,对症下药。
糖尿病足骨髓炎(Diabetic foot osteomyelitis,DFO)与更高的踝上截肢率相关。尽管DFO有着很高的发生率和糟糕的预后,然而针对其治疗却缺乏高质量的证据。由于缺乏基于证据的指南,导致其治疗方法多种多样。作者咨询了14个外科专家,采用Delphi方法获得了关于DFO诊断、治疗和管理的专家共识。同时作者希望有更多有力的研究和更清晰的指南,以便能改善外科治疗的结果。
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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