Merve Tomas1 , Deniz Günal-Köroğlu1 , Senem Kamiloglu2,3, Tugba Ozdal4 and Esra Capanoglu1,5*
*Correspondence: Esra Capanoglu 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
1 Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, 34469 Maslak, Istanbul, Türkiye
2 Department of Food Engineering, Faculty of Agriculture, Bursa Uludag University, 16059 Gorukle, Bursa, Türkiye
3 Science and Technology Application and Research Center (BITUAM), Bursa Uludag University, 16059 Gorukle, Bursa, Türkiye
4 Department of Food Engineering, Faculty of Engineering and Natural Sciences, Istanbul Okan University, 34959 Tuzla, Istanbul, Türkiye
5 School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China
Abstract
Phytochemicals help mitigate skin aging by scavenging free radicals, modulating key enzymatic pathways, and promoting the skin’s structural integrity. Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase, collagenase, and elastase, which degrade skin structure, and reducing levels of inflammatory markers (IL-6, IL-8, etc.) and matrix metalloproteinases (MMP-1, MMP- 2) linked to aging. Recent research highlights that plant-based phytochemicals can improve skin elasticity, reduce hyperpigmentation, prevent the breakdown of important skin proteins, and support wound healing, making them valuable components for skin care and treatments. This review explores the multifaceted roles of phytochemicals in maintaining and improving skin health, highlighting their mechanisms of action and potential in skin anti-aging
Keywords Skin care, Anti-aging, Phytochemicals, Polyphenols, Carotenoids, Fatty acids, Saponins, Alkoloids
封红伟 陈丽琴 胡绣华
DOI：10.3969/j.issn.0253-9926.2020.21.004
基金项目：上海市宝山区科学技术委员会科技创新专
项资金项目(17-E-8)
作者单位：200940 上海市第一人民医院宝山分院护理
部
【摘 要】 目的 观察次氯酸消毒液联合湿性愈合方法在慢性伤口中的效果。方法 对 2017 年 1 月至 2019 年 5 月在我院伤口门诊就诊慢性伤口患者(150 例 229 处伤口)，采用随机数字表格法分为观察组(75 例 116 处伤口)，采用次氯酸消毒液联合湿性愈合方法；对照组(75 例 113 处伤口)，采用常规湿性换药方法。比较 2 组患者创面愈合率、愈合时间、换药次数。 结果 观察组的伤口愈合率高于对照组，愈合时间、换药次数均少于对照组，差异有统计学意义(P<0．05)。结论 应用次氯酸消毒液联合湿性愈合方法优于常规湿性愈合方法。
【关键词】 次氯酸；消毒药；伤口愈合
Observation on the curative effect of hypochlorite disinfectant combined with wet healing on chronic wounds
Feng Hongwei, Chen Liqin, Hu Xiuhua．Department of Nursing， Baoshan Branch of Shanghai First People′s Hospital，Shanghai 200940， China
【Abstract】 Objective
To observe the effect of hypochlorite disinfectant combined with wet healing on chronic wounds．
Methods
From January 2017 to May 2019 229 wounds in 150 patients with chronic wounds were randomly divided into two groups： the observation group (116 wounds in 75 patients) of using combination of hypochlorite disinfectant and wet healing method and the control group (113 wounds in 75 patients) of using conventional wet healing method． Wound healing rate， healing time and dressing change times between the two groups were compared． Results The wound healing rate of the observation group was higher than that of the control group (P < 0．05)， and the healing time and dressing change times of the observation group were also lower than those of the conventional group (P< 0．05)． Conclusion
The combination of hypochlorite disinfectant and wet healing method is better than the conven
tional wet healing method．
【Key words】 Hypochlorous acid； Disinfectants； Wound healing
原创： 十六点五 中山二院糖尿病足中心
2019年1月22日，对患者的足进行了第一次清创，效果如下：
由于各种原因，患者到中心的合作医院治疗了整整两个星期。在不断的微信沟通下，合作医院的医生进行了不懈的努力，患者继续向保足的方向又前进了几步。
周末很快就过去了，今天才想办法将病人收入病房，这两天在病房护士的帮助下，进行安尔碘纱布填塞换药，借助急诊科的留观床进行内科治疗，控制血糖、全身抗生素、监测全身重要脏器功能、营养支持等，由于患者脓液被充分引流，局部炎症反应有所消除，患者全身炎症反应（SIRS）明显改善。
进入冬季
广州的气温进入了“过山车”阶段
扫倒了无数的病人
“糖尿病足”病人的数量毫无悬念地进入了高峰
周末，可怕的周末
好像严重的糖尿病足的病人
只有到了周末才想起我们
同样的剧本在此再次展开了恐怖的幕布
伤口世界平台生态圈，以“关爱人间所有伤口患者”为愿景，连接、整合和拓展线上和线下的管理慢性伤口的资源，倡导远程、就近和居家管理慢性伤口，解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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