A.Giaccari1 · G. Gliozzo1 · G. Ciccarelli1 · G. Di Giuseppe1 · C. Castellano2 · S. Cum3 · L. Delle Monache4,13 · M. Gallo5 ·M.Lastretti6 · G. Medea7 · M. Monesi8 · R. Napoli9 · B. Pintaudi10 · E. Succurro11 · G. Turchetti
Received: 9 January 2026 / Accepted: 17 March 2026 © The Author(s) 2026
Abstract
Background and aims Although continuous glucose monitoring (CGM) devices are now standard of care among Type 1 diabetes patients, they are still relatively underutilized in Type 2 diabetes (T2D), particularly in those patients not treated with insulin. Widespread adoption continues to be hindered by a combination of factors. Chief among these is the scarcity of long-term, large-scale clinical trials demonstrating the benefits of the use of CGM in T2D. This meta-analysis aimed to address this gap by comparing CGM with self-blood glucose monitoring (SBMG), with primary outcomes of HbA1c and time in range (TIR) in insulin-treated and non-insulin-treated TD2 patients.
Methods and results Following the stringent rules mandated by our National Health Service (which requires a panel com-posed of all stakeholders involved in diabetes treatment, and includes PICO, GRADE, AGREE, and meta-analyses), we performed a systematic review of RCTs that enrolled two groups of individuals with T2D, those treated with insulin (includ-ing basal and basal-bolus regimens), and those receiving treatments other than insulin. All included trials compared CGM with structured blood glucose monitoring (SBGM) with glycated hemoglobin (HbA1c) as the main endpoint. Based on the strength and consistency of the evidence, the panel issued a strong recommendation in favor of CGM for individuals with T2D treated with insulin (including those on basal insulin alone) and for individuals with T2D not treated with insulin, par-ticularly for those with glycated hemoglobin levels≥7%. From a pharmacoeconomic perspective, outcomes were positive in both patient groups.
Conclusion CGM represents a clinically effective and cost-efficient approach to optimizing glycemic control in T2D, becom-ing mandatory among individuals on insulin therapy. Our findings support a shift in clinical practice toward the more widespread use of CGM in T2D, with regulatory frameworks and reimbursement policies needing to adapt accordingly.
Keywords CGM · Type 2 Diabetes · Metanalysis · PICO · GRADE · Guidelines
Communicated by Massimo Federici, M.D.
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1 Center for Endocrine and Metabolic Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS and Università Cattolica del Sacro Cuore, Rome, Italy
2 Azienda USL of Modena, Sassuolo Hospital, Sassuolo, Italy
3 Diabetes and Diabetic Foot Care Unit, ASUGI, Monfalcone, Italy
4 National Board Member of FAND (Italian Association for the Rights of Diabetic People), Roma, Italy
5 Department of Endocrinology and Metabolic Diseases, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
6 Order of Psychologists of Lazio, Rome, Italy
7 Italian Society of General Medicine (SIMG), Florence, Italy
8 Territorial Diabetology Unit, AUSL Ferrara, Ferrara, Italy
9 Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
10 Diabetes Unit, Niguarda Cà Granda Hospital, Milan, Italy
11 Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
12 Institute of Management, Scuola Superiore Sant’Anna, Pisa, Italy
13 Patient Advocacy Lab, ALTEMS – Università Cattolica del Sacro Cuore, Rome, Italy
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引用本文:简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.
通信作者:邓呈亮,Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
ABSTRACT: Pressure ulcers generally occur at body sites where there are sustained soft tissue stress concentrations associated with either bodyweight or medical devicerelated mechanical forces. These sustained mechanical forces caused by pressure and shear result in localised tissue/cell distortion. This leads to deformation-induced damage, inflammation and ischemia resulting in tissue death and, ultimately, a pressure ulcer (Katz and Gefen, 2023).
In order to reduce the risk of pressure damage occurring, it is common in clinical practice to select a pressure redistributing support surface (mattress or cushion). It is also important to reposition the patient in order to both change the areas that are load bearing and — as much as possible — increase the surface area of the body that is supporting the load, while avoiding positioning on the most at-risk areas, for example the bony prominences.
KEY WORDS
Interface pressure
Pressure mapping
Pressure ulcer
JACQUI FLETCHER
Independent Nurse Consultant
ABSTRACT: In order to provide structured and equitable interventions in relation to identification and management of wound infection, an NHS Trust has implemented an evidence-based pathway for non-healing wounds. Following the introduction of the pathway there were reduced nurse visits for wound assessment, a reduction in wound area, a reduction in necrotic tissue and improved healing rates.
Case study
Evidence
Infection
Pathway
Silver dressing
UrgoClean Ag
Wound
ANITA KILROY-FINDLEY, Clinical Lead Tissue Viability, Leicestershire Partnership NHS Trust
KAREN OUSEY, PhD, Professor of Skin Integrity, Institute of Skin Integrity and Infection Prevention, University of Huddersfield
Objective: This article highlights challenges of wound care in low resource settings, considering opportunities for frugal innovation and our experiences while creating virtual wound care clinics across two global communities. In addition, we will discuss four real cases presented within the virtual clinics. An adaptation of the widely accepted tissues, infection, moisture, edge, regeneration and repair of tissue, and social factors (TIMERS) wound assessment is also proposed with considerations for low-resource setttings.
Method: From March to December 2021 the University of Salford engaged in a virtual wound clinic initiative with colleagues in Fort Portal Regional Referral Hospital.
Results: The clinics provided opportunities for professional and academic development of students on postgraduate tissue viability module in Salford, while empowering nurses and midwives in Uganda in taking their place at the centre of multidisciplinary teams in care delivery Furthermore, it created links between the university and clinicians in Uganda to develop the delivery of evidence-based wound management. Throughout this period, challenges associated with low resources were highlighted and, in some cases, innovative approaches to managing wound care were adopted to account for this.
Conclusions: The development and delivery of the virtual wound care clinics between the University of Salford and Fort Portal Regional Referral Hospital provided an opportunity for reflection on practice. This led to development of a Fit4purpose wound dressing, revision of evidence-based guidelines, deeper understanding of the scarcity of essential items and frugal practice, and examination of skin tone bias in the signs and symptoms of wound infection in patients with dark skin tones.
Case series
Dressings
Frugal innovation
Low resource
Uganda
Wounds
DR MELANIE STEPHENS
PhD, RGN, Senior Lecturer in Adult Nursing and Lead for Interprofessional Education, School of Health and Society, Mary Seacole Building, University of Salford, UK
MATTHEW WYNN,
MSc, RN Adult, Lecturer in Adult Nursing, School of Health and Society, Mary Seacole Building, University of Salford, UK
SHEBA PRADEEP
LOUISE ACKERS
Chair in Global Social Justice, Director Knowledge, Health and Place Research
RACHEL NAMIRRO
Registered Midwife, Assistant Nursing Officer, Knowledge for Change, Fort Portal, Kabarole District, Uganda
BECKY MASKEW,
BSc Nursing (Adult), Staff nurse, Fairfield General Hospital, Northern Care Alliance, UK
SARAH SULEIMAN
Student Nurse CYP, School of Health and Society, Mary Seacole Building, University of Salford, UK
JANE BOARDMAN, BA Hons, Student Nurse, School of Health and Society, Mary Seacole Building, University of Salford, UK
DEREK BAHANDAGIRA, Registered Nurse, Assistant Nursing Officer, Surgical, Paediatrics, and Diabetes Clinic, Fort Portal Regional Referral Hospital, Uganda
ANGELA MUGUMBA,
Certificate of Registration Midwife, Assistant Nursing Officer, Knowledge for Change, Labour/Gynaecology Ward, Fort Portal Regional Referral Hospital, Uganda
KAYLEIGH THORNTON,
MA, Registered Midwife, Stockport Foundation Trust, UK AUGUSTINE SSEMUJJU, MMed (Obstetrics & Gynaecology), Specialist in Obstetrics and Gynaecology, Fort Portal Regional Referral Hospital, Uganda
YASMIN CAPEL, MBBS, Doctor, Knowledge for Change, Fort Portal Regional Referral Hospital, Uganda ODUR JOE, BSc, Pharmacist, Fort Portal Regional Referral Hospital, Pharmacy Stores
NALUKENGE PROSCOVIA,
Senior Theatre Assistant, Fort Portal Regional Referral Hospital, Uganda
HANNAH RANK, MBChB,
Doctor, Knowledge for Change, Fort Portal, Kabarole District, Uganda
AGNIESZKA SZYMKOWIAK,
MSc, CYP Nurse, Guy's and St Thomas NHS Trust, UK
JACQUI FLETCHER OBE
Senior Clinical Advisor Stop the Pressure Programme/National Wound Care Strategy NHS England Clinical Implementation Manager
Surgical wound dehiscence (SWD), a complication of surgery, can delay wound healing, increase the economic burden of the healthcare provider, and have a negative impact on the patient’s wellbeing. The fundamental goal for the treatment of SWD is wound closure. This article describes the use of Avance® Solo, a negative pressure wound therapy system, selected as a therapy for both the prevention and treatment of dehisced closed surgical incision wounds in a patient with complex and social needs.
Negative pressure wound therapy (NPWT)
Patient wellbeing
Surgical wound dehiscence
Wound healing
LISA SUTHERLAND
MSC RN LLB(HONS), Nurse Consultant for Wound Management and Tissue Viability, Norfolk anad Norwich University Hospital; Honorary Lecturer, University of East Anglia, Norwich, UK
N Rezai
The Covid-19 pandemic, with its disruption of services and higher mortality risk has had far-reaching consequences for people with diabetes, contributing toward increased risk of rapid deterioration, ICU admissions and a worse prognosis. Covid-19 also affected access to diabetes related foot care and multidisciplinary services, with long-term implications for people who were unable to access care and attend clinic appointments during the pandemic. This review examines studies on the effect of Covid-19 on people with diabetes, foot complications associated with diabetes and service delivery.
Citation: Rezai N (2023) What are the effects of Covid-19 on diabetes and diabetic foot-related complications?. The Diabetic Foot Journal 26(1): 40–5
Key words
- Covid-19
- Foot care access
- Service provision
- Telemedicine
Article points
1. People with diabetes are more likely to be more unwell with Covid-19.
2. Foot care services were severely disrupted during the pandemic.
3. Lessons learned from the pandemic give avenues to investigate for footcare services in future.
Author
Miss Nealoofar Rezai, BSc (Hons) MRCPod, is Clinical Lead Podiatrist, Royal Free Hospital, London, UK
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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