A.Giaccari1 · G. Gliozzo1 · G. Ciccarelli1 · G. Di Giuseppe1 · C. Castellano2 · S. Cum3 · L. Delle Monache4,13 · M. Gallo5 ·M.Lastretti6 · G. Medea7 · M. Monesi8 · R. Napoli9 · B. Pintaudi10 · E. Succurro11 · G. Turchetti
Received: 9 January 2026 / Accepted: 17 March 2026 © The Author(s) 2026
Abstract
Background and aims Although continuous glucose monitoring (CGM) devices are now standard of care among Type 1 diabetes patients, they are still relatively underutilized in Type 2 diabetes (T2D), particularly in those patients not treated with insulin. Widespread adoption continues to be hindered by a combination of factors. Chief among these is the scarcity of long-term, large-scale clinical trials demonstrating the benefits of the use of CGM in T2D. This meta-analysis aimed to address this gap by comparing CGM with self-blood glucose monitoring (SBMG), with primary outcomes of HbA1c and time in range (TIR) in insulin-treated and non-insulin-treated TD2 patients.
Methods and results Following the stringent rules mandated by our National Health Service (which requires a panel com-posed of all stakeholders involved in diabetes treatment, and includes PICO, GRADE, AGREE, and meta-analyses), we performed a systematic review of RCTs that enrolled two groups of individuals with T2D, those treated with insulin (includ-ing basal and basal-bolus regimens), and those receiving treatments other than insulin. All included trials compared CGM with structured blood glucose monitoring (SBGM) with glycated hemoglobin (HbA1c) as the main endpoint. Based on the strength and consistency of the evidence, the panel issued a strong recommendation in favor of CGM for individuals with T2D treated with insulin (including those on basal insulin alone) and for individuals with T2D not treated with insulin, par-ticularly for those with glycated hemoglobin levels≥7%. From a pharmacoeconomic perspective, outcomes were positive in both patient groups.
Conclusion CGM represents a clinically effective and cost-efficient approach to optimizing glycemic control in T2D, becom-ing mandatory among individuals on insulin therapy. Our findings support a shift in clinical practice toward the more widespread use of CGM in T2D, with regulatory frameworks and reimbursement policies needing to adapt accordingly.
Keywords CGM · Type 2 Diabetes · Metanalysis · PICO · GRADE · Guidelines
Communicated by Massimo Federici, M.D.
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1 Center for Endocrine and Metabolic Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS and Università Cattolica del Sacro Cuore, Rome, Italy
2 Azienda USL of Modena, Sassuolo Hospital, Sassuolo, Italy
3 Diabetes and Diabetic Foot Care Unit, ASUGI, Monfalcone, Italy
4 National Board Member of FAND (Italian Association for the Rights of Diabetic People), Roma, Italy
5 Department of Endocrinology and Metabolic Diseases, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
6 Order of Psychologists of Lazio, Rome, Italy
7 Italian Society of General Medicine (SIMG), Florence, Italy
8 Territorial Diabetology Unit, AUSL Ferrara, Ferrara, Italy
9 Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
10 Diabetes Unit, Niguarda Cà Granda Hospital, Milan, Italy
11 Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
12 Institute of Management, Scuola Superiore Sant’Anna, Pisa, Italy
13 Patient Advocacy Lab, ALTEMS – Università Cattolica del Sacro Cuore, Rome, Italy
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引用本文:简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.
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Andrew Hill
This article explores the growing role of artificial intelligence (AI) in patient self care in diabetes and considers the opportunities and risks associated with it in the context of foot self care in diabetes. AI has yielded many advances in individual and public health, although it does also present unique and emergent challenges. Certainly, AI enables us to consider and re-evaluate diabetes care, screening and management.
Hill A (2023) Is artificial intelligence the key to better foot self-care in diabetes? The Diabetic Foot Journal 26(2): 24–8
Key words
- Artificial intelligence
- Patient knowledge
- Self care
- Technology
Article points
1. Artificial intelligence has been shown to influence and improve certain aspects of diabetes care.
2. Self care and patient education are key to avoiding complications such as diabetic foot ulcers.
3. Artificial intelligence has as-yet unleashed potential in the field of foot self care and ulcer management, especially in the context of patient education and driving foot self-care behaviours.
Author
Andrew Hill is Senior Lecturer and Programme Lead The SMAE Institute.
In December 2023, NICE published the TA943 guidance, which lays out recommendations for use of hybrid closed-loop (HCL) systems in the management of type 1 diabetes, with a 5-year roll-out plan.1 Even with moderate adoption rates, NICE anticipates that over 57 000 people with type 1 diabetes will end up accessing this technology. Although the treatment and care of people using HCL technology sits within specialist multidisciplinary teams, there are elements of care that are useful for primary care clinicians to know. This factsheet explains what HCL systems are and outlines what primary healthcare professionals need to know to support their use.
Louise Morris, Jayne Robbie, Duncan Stang, Catherine Bewsey, Andrew Sharpe, Christian Pankhurst, Krishna Gohil and Michael Edmonds
A crucial barrier to effective diabetic foot care is the delay in accessing specialist care. Delays can take place in three situations:
1. Delay by the person with diabetes in seeking care. A lack of knowledge in the person with diabetes can lead to a lack of urgency in seeking help from a healthcare professional.
2. Delay by healthcare professionals in referring to specialist care. When a person with a foot problem seeks advice, there is sometimes a delay due to failure of a healthcare professional to make a diagnosis
3. Delay in accessing care related to the multidisciplinary diabetic foot team. Referrals from primary and community care to the multidisciplinary foot team are difficult if it meets infrequently or does not exist and that is the situation in some
Hospital Trusts in the UK. Four recommendations to reduce delays are put forward:
1 Formation of a credible multidisciplinary diabetic foot team.
2. Organisation of efficient referral pathways.
3. Establishment an advanced/consultant podiatrist role.
4 Utilisation of the ACT NOW acronym as a triage tool to highlight warning signs leading to amputation.
Citation: Morris L, Robbie J, Stang D et al (2023) Delays in getting to specialist care for people with diabetes and foot problems. What are the delays and how can we reduce them — a Position Statement from the ZAP Amputation group of FDUK. The Diabetic Foot Journal 26(2): 29–38
- Amputation
- Delays
- Diabetes-related ulcers
- Specialist care
1. Initial assessment of foot problems in diabetes is carried out in community or primary care. It is, therefore, vital that referral routes for the PwD are robust and well-known to ensure rapid access to the MDFT
2. Delays in accessing specialist MDFT can have catastrophic outcomes for the PwD in terms of tissue loss, amputation and/or early mortality
3. Advanced/consultant podiatrist roles should be developed within each hospital Trust to co-ordinate foot care services for a PwD
4. ACT NOW is a simple, six-stage triage tool to empower the PwD and HCPs to determine if a foot problem requires
Authors
See page 30
Louise Morris is Principal Podiatrist, Trafford Local Care Organisation Podiatry Department, Trafford General Hospital, Manchester, UK; Jayne Robbie is Senior Podiatrist, University Hospitals Birmingham NHS Trust; Senior Lecturer, Birmingham City University; Duncan Stang is National Diabetes Foot Co-ordinator, Scotland; Catherine Bewsey is Chartered Counselling Psychologist, SWL ICS Foot Network Project, St George’s University Hospitals NHS Foundation Trust; Andrew Sharpe is Advanced Podiatrist, Salford Royal NHS Foundation Trust, UK; Christian Pankhurst is Lead Orthotist, Kings College Hospital, NHS Foundation Trust, London, UK; Krishna Gohil is National Clinical Lead, Lower Limb Wounds National Woundcare Strategy Programme, UK; London, UK; Michael Edmonds is Consultant Diabetologist, Diabetic Foot Clinic, King’s College Hospital, London, UK
David Morris, Probal Moulik
Symptoms of pancreatic cancer often present late, and most are non-specific and thus misinterpreted Although a rare condition, the prognosis for pancreatic cancer is very poor, with a 5-year survival rate of 7.3%; however, this improves to 30% for early-stage diagnosis Prediabetes or diabetes are found in around 80% of people diagnosed with pancreatic carcinoma and, importantly, are often identified a year or two ahead of this diagnosis Thus, new-onset diabetes represents an opportunity for early detection of pancreatic carcinoma. Through this case report of an older gentleman with new-onset diabetes and a normal BMI, the authors discuss how healthcare professionals can identify people who might be at risk of pancreatic cancer, along with the differential diagnoses, and what actions they should take.
David Morris, Retired GP and Specialist Doctor in Diabetes, Undergraduate Clinical Tutor, Keele University; Probal Moulik, Consultant Endocrinologist, Shrewsbury and Telford Hospitals NHS Trust.
Citation: Morris D, Moulik P (2023) Case report: Pancreatic cancer – assessing diabetes in a thin elderly person. Diabetes & Primary Care 26: [Early view publication]
Habitual calcium supplementation is associated with an increased risk of cardiovascular disease (CVD) amongst people with diabetes but not in those without diabetes, according to this study of UK Biobank data published in Diabetes Care. Over a median follow-up of 8.1 years, 26 374 cardiovascular events were recorded amongst the 435 000 participants studied, and over a median follow-up of 11.2 years there were 20 526 deaths, of which around 4000 were designated as cardiovascular deaths. Amongst those with diabetes, habitual calcium supplementation was significantly associated with higher risks of cardiovascular events (HR 1.34), cardiovascular mortality (HR 1.67) and all-cause mortality (HR 1.44) compared to no calcium supplementation. In contrast, calcium supplementation in those without diabetes was not associated with significantly increased risk of these outcomes. Since habitual calcium supplementation is common in older people keen to reduce the risk of osteoporotic fractures, and since cardiovascular risk is already higher in those with diabetes, any potential increases in risk of CVD or other adverse events associated with calcium supplementation are important.
Pam Brown
GP in Swansea
Citation: Brown P (2024) Diabetes Distilled: Calcium supplementation in people with diabetes – is caution needed? Diabetes & Primary Care 26: [Early view publication]
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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