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03 9月 2019

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Author : 伤口世界

擅长造口护理、造口并发症处理，对外科术后感染伤口、肿瘤伤口、下肢动/静脉溃疡、失禁、瘘管、糖尿病溃疡足、放射性皮炎及其他慢性疑难伤口处理均具有丰富的经验。

国际造口/伤口失禁治疗师（ET），东莞康华医院普外科护士长，广东省护士协会第一届伤口造口失禁护士分会常委，广东省家庭医师协会护理分会第一届委员常务委员会委员，广东省家庭医生协会护理分会第一届委员，康华医院伤口/造口/失禁专科护理质量管理副组长。参与东莞市科技进步奖一等奖课题一项，主持及参与市级课题3项，发表科研论文4篇，2015年获广东省伤口造口PPT演讲比赛第一名，2017在东莞市护理学会举办“东莞市伤口护理病例大赛”中荣获优胜奖。东莞市伤口造口实习基地带教老师、

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Implantable biomedical materials for treatment of bone infection 2026-03-02 00:00

Wang Shuaishuai 1† , Zhu Tongtong1† , Wang Dapeng2 ,

Zhang Mingran1 , Wang Xukai 1 , Yu Yue1 , Dong Hengliang1 ,

Wu Guangzhi 1 * and Zhang Minglei 1 *

1 Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China,

2 Department of Orthopedics, Siping Central Hospital, Siping, China

EDITED BY

Xiaoyuan Li,

Northeast Normal University, China

REVIEWED BY

Fuzeng Ren,

Southern University of Science and

Technology, China

Gong Cheng,

Harvard University, United States

Ruogu Qi,

Nanjing University of Chinese Medicine,

China

*CORRESPONDENCE

Wu Guangzhi,

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Zhang Minglei,

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†

These authors have contributed equally to this work

SPECIALTY SECTION

This article was submitted to Biomaterials, a section of the journal

Frontiers in Bioengineering and Biotechnology

RECEIVED 27 October 2022

ACCEPTED 18 January 2023

PUBLISHED 30 January 2023

CITATION

Shuaishuai W, Tongtong Z, Dapeng W, Mingran Z, Xukai W, Yue Y, Hengliang D, Guangzhi W and Minglei Z (2023), Implantable biomedical materials for treatment of bone infection.

Front. Bioeng. Biotechnol. 11:1081446.

doi: 10.3389/fbioe.2023.1081446

COPYRIGHT

© 2023 Shuaishuai, Tongtong, Dapeng, Mingran, Xukai, Yue, Hengliang, Guangzhi and Minglei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).

The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

The treatment of bone infections has always been difficult. The emergence of drugresistant bacteria has led to a steady decline in the effectiveness of antibiotics. It is also especially important to fight bacterial infections while repairing bone deffects and cleaning up dead bacteria to prevent biofilm formation. The development of biomedical materials has provided us with a research direction to address this issue.

We aimed to review the current literature, and have summarized multifunctional antimicrobial materials that have long-lasting antimicrobial capabilities that promote angiogenesis, bone production, or “killing and releasing.” This review provides a comprehensive summary of the use of biomedical materials in the treatment of bone infections and a reference thereof, as well as encouragement to perform further research in this field.

KEYWORDS

biological materials, bone infection, multifunctional material, implantable material, treatment of bone infection, progress of infection treatment, multifunctionalization of materials
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