2023中国临床实践指南:雄激素性脱发诊断与治疗

中华医学会整形外科学分会中国雄激素性脱发诊断与治疗指南制订工作组整形美容 .
专业国家级医疗质量控制中心中国整形美容协会毛发 医学分会中 国女医师协会.
整形美容专业委员会
通信作者:张菊芳,西湖大学医学院附属杭州市第一人民医院医疗美容科,杭州310006, Email: zhjuf@ vip. sina. com;

吴文育,复旦大学附属华山医院皮肤科,上海200040, Email: wuwenyu@ huashan. org. cn;

牛冬,浙江农林大学动物科技学院、动物医学院,杭州311300, Email: dniu@ zafu. edu.cn;

龙笑,中国医学科学院北京协和医学院北京协和医院整形外科,北京100032, Email: pumclongxiao@ 126. com.

[摘要] 雄激素性脱发发病率逐年增高并呈现低龄化的趋势,困扰着众多患者。对于雄激素性脱发的治疗,近年来出现了很多新方式和思路，因此雄激素性脱发的治疗策略需要随之更新;另外,随着近年来毛发行业的发展,大量的从业者涌人雄激素性脱发诊治的相关岗位,因此需要经过证实的指南来进行指引。指南制订工作组遴选了有关临床问题，经过证据检索、专家论证,形成了相关推荐意见,以期能够进一步规范雄激素性脱发的治疗决策。

[关键词] 脱发;雄激素性脱发; 整形外科;指南
基金项目:杭州市医学重点学科( 002020004);上海市级医院皮肤科临床能力促进与提升专科联盟(SHDC22022302);上海市重中之重研究中心建设项目(2023702018);上海毛发医学工程技术研究中心(19D22250500);浙江省自然科学基金重点项目(LZ22C010003);北京协和医院中央高水平医院临床科研专项( 2022-PUMCH-B-042)

DOI: 10. 3760/ema. j. en1 14453-20231029-00156

Chinese guideline for the diagnosis and treatment of androgenetic alopecia ( 2023)

The Working Group of Chinese Guideline for the Diagnosis and Treatment of Androgenetic Alopeeia, Chinese Medical Association of Plastic Surgery; National Medical Quality Control Center for Plastic Surgery; Society of Hair Medicine, Chinese Association of Plastics and Aesthetics; Plastic & Aesthetic Surgery Comitee, China Medical Women 's Association

Corresponding author: Zhang Jufang， Department of Medical Cosmetology， Hangzhou First People' s Hospital, Westlake University, Hangzhou 310006， China, Email: zhjuf@ rip. sina. com; Wu Wenyu,
Department of Dermatology, Huashan Hospital, F'udan University, Shanghai 200040， China， Email: wuwenyu@ huashan. org. cn; Niu Dong, Animal Science College and Animal Medicine College , Zhejiang
A&F University , Hangzhou 311300，China, Email: dniu@ zafu. edu. cn; Long Xiao, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100032, China ，Email: pumclongxiao@ 126. com

[ Summary] The incidence rate of androgenetice alopecia is increasing year by year and presents a trend of younger age, which puzzles many patients. In recent years, there have been many new treatment
methods and ideas for androgenetic alopecia, so the treatment strategies for androgenetic alopecia need to be : updated accordingly. In addition, with the development of the hair industry in recent years, a large number of practitioners have flocked to positions related to the diagnosis and treatment of androgenetie alopecia, so proven guidelines are needed for guidance. The guide writing team selected relevant clinical issues, gave recommendations based on a thorough literature review of the latest reports and expert' s evaluation, in the hope of providing a treatment algorithm for androgenetic alopecia.

[Key words] Alopecia; Androgenetic alopecia; Plastie surgery; Guideline

Fund program: Hangzhou Key Discipline of Medieine ( 0020200044 ) ; Shanghai M unicipal Hospital Dermatology Clinical Ability Promotion and Enhancement Specialist Alliance .
( SHDC22022302) ; Shanghai Most Important Research Center Construction Project ( 2023Z702018) ; Shanghai Hair Medical Engineering Technology Research Center ( 19DZ2250500); Zhejiang Province
Natural Science Foundation Key Project ( LZ22C010003 ); National High Level Hospital Clinical Research Funding ( 2022-PUMCH-B-042)

Disclosure of Conflicts of Interest: The authors have no financial interest to declare in relation to the content of this article.

DOI: 10. 3760/ ema. j. en1 14453-2023 1029-00156

中国敏感性皮肤诊治专家共识

何黎1 ，郑捷2 ，马慧群3 ，郝飞4 ，刘玮5 ，王刚6 ，李利7 ，高兴华8 ，项蕾红9 ，吴艳1 0 ，谢红付11 ，袁超12 ，林彤13 ，赖维14 ，刘盛秀1 5 ，张丽8 ，李吉1 1 ，严淑贤9 ，崔勇16 ，李虹17 ，陈抗18 ，周展超19 ，钟莉20 ，梁虹2 1 ，骆丹2 2 ，卢凤艳23 ，熊霞24 ，庞勤2 5 ，王玮蓁26 ，王秀丽12 ，朱丽萍1

［中图分类号］ Ｒ 593． 1

［文献标识码］ A

［文章编号］ 1001 － 7089( 2017) 01 － 0001 － 04

［DOI］ 10. 13735 /j. cjdv. 1001-7089. 201611168

［基金项目］ 云南省“高原皮肤病防治转化医学协同创新中心”( 601160707) ; 教育部 2013 年度“创新团队发展计划”( ＲIT13067) 资助项目

［作者单位］ 1． 昆明医科大学第一附属医院，云南 昆明 650032;

2． 上海交通大学附属瑞金医院，上海 200240;

3． 西安交通大学第二附属医院，陕西西安710000;

4． 第三军医大学第一附属医院( 西南医院) ，重庆400038;

5． 北京空军总医院，北京100142;

6． 第四军医大学西京医院，陕西 西安710000;

7． 四川大学华西医院，四川 成都610041;

8． 中国医科大学附属第一医院，辽宁 沈阳110001;

9． 复旦大学附属华山医院，上海200040;

10． 北京大学第一医院，北京 100034;

11． 中南大学湘雅医院，湖南 长沙 410008;

12． 上海市皮肤病医院，上海 200443;

13． 中国医学科学院皮肤病医院，江苏 南京210042;

14． 中山大学附属第三医院，广东 广州 510630;

15． 安徽医科大学附属医院，安徽 合肥 230032;

16． 中日友好医院，北京 100029;

17． 昆明薇诺娜皮肤医疗美容有限公司，云南 昆明 650031;

18． 海南省皮肤病医院，海南 海口 570000;

19． 南京展超丽格医疗美容诊所，江苏 南京 210000;

20． 重庆大学附属医院，重庆 400038;

21． 武汉大学人民医院，湖北 武汉 430060;

22． 南京医科大学第一附属医院，江苏 南京 210029;

23． 曲靖市第一人民医院，云南 曲靖 655000;

24． 西南医科大学附属中医医院，重庆 400038;

25． 天津市中医药研究院附属医院( 长征医院) ，天津 300120;

26． 武汉市第一医院，湖北 武汉 430070

［学术秘书］ 朱丽萍，E-mail: 13529062890@ 103． com

A New Ten-item Questionnaire For Assessing Sensitive Skin: The Sensitive Scale-10

Laurent Misery 1,2 , Catherine Jean-Decoster3 , Sophie Mery 3 , Victor Georgescu 3 and Vincent Sibaud 3 1 Laboratory of Neurosciences of Brest, University of Western Brittany, 2 Department of Dermatology, University Hospital of Brest, Brest, and 3 Dermatological Laboratories Avène, Lavaur, France

      Sensitive skin is common but until now there has been no scale for measuring its severity. The Sensitive Scale is a new scale with a 14-item and a 10-item version that was tested in 11 countries in different languages on 2,966 participants. The aim of this study was to validate the pertinence of using the Sensitive Scale to measure the severity of sensitive skin. The internal consistency was high. Correlations with the dry skin type, higher age, female gender, fair phototypes and Dermatology Life Quality Index were found. Using the 10-item version appeared to be preferable because it was quicker and easier to complete, with the same internal consistency and the 4 items that were excluded were very rarely observed in patients. The mean initial scores were around 44/140 and 37/100. The use of a cream for sensitive skin showed the pertinence of the scale before and after treatment. Key words: sensitive skin; DLQI; scale; severity; questionnaire.

Accepted Apr 2, 2014; Epub ahead of print Apr 7, 2014

Acta Derm Venereol 2014; 94: 635–639.

Prof Laurent Misery, Department of Dermatology, University Hospital of Brest, 2 avenue Foch, FR-29200 Brest, France. E-mail: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

© 2014 The Authors. doi: 10.2340/00015555-1870 Journal Compilation © 2014 Acta Dermato-Venereologica. ISSN 0001-5555

｜开放获取·指南与共识｜保湿润肤类产品应用指导专家共识（2023版）

茶叶预防衰老及衰老相关疾病研究进展

戴申，鹿颜，余鹏辉，龚雨顺*，刘仲华*

湖南农业大学园艺园林学院，国家植物功能成分利用工程技术研究中心，茶学教育部重点实验室，湖南 长沙 410128

摘要：综述了茶叶及其主要功能成分茶多酚、茶氨酸和咖啡碱对秀丽线虫、果蝇及老鼠等多种模式生物的抗衰老作用；概述了茶叶预防衰老相关疾病的保健功能；阐述了茶叶通过调节能量感应网络延缓衰老的研究现状；简单讨论了今后茶叶抗衰老研究的方向。

关键词：茶；抗衰老；能量感应网络

中图分类号：S571.1 文献标识码：A 文章编号：1000-369X(2019)01-023-11

Research Progress of The Preventing Effects of Tea on Aging and Aged-related Pathologies

DAI Shen, LU Yan, YU Penghui, GONG Yushun*, LIU Zhonghua*

Hunan Agriculture University, College of Horticulture and Landscape, National Engineering Center of Plant Functional Components Utilization, Key Lab of Tea Science, Changsha 410128, China

Abstract: In this paper, the anti-aging effects of tea in model organisms such as Caenorhabditis elegans, Drosophila flies and mice were reviewed. The main functional components (tea polyphenols, theanine and caffeine) were especially emphasized. The beneficial functions of tea in preventing age-related diseases were summarized. Furthermore, the latest research on its mechanism of regulating the nutrient-sensing signaling networks was expounded. Finally, the future research direction was briefly discussed.

Keywords: tea, anti-aging, nutrient-sensing signaling networks

收稿日期：2018-08-27 修订日期：2018-09-20

基金项目：湖南省自然科学基金（No. 2018JJ2161）

作者简介：戴申，女，硕士研究生，主要从事茶叶功能成分化学研究。*通信作者：该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。，该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

Diabetes remission in the real world

Pam Brown

GP in Swansea

Citation: Brown P (2024) Diabetes Distilled: Diabetes remission in the real world. Diabetes & Primary Care 26: 145–7

      Diabetes remission is achievable at scale in the real world, according to early results from the NHS Type 2 Diabetes Path to Remission programme published in Lancet Diabetes & Endocrinology. Of 7540 people referred to the programme between September 2020 and December 2022, a total of 1740 started the total diet replacement section of the programme before January 2022, and 960 (55%) completed the programme. Mean weight loss for the 1710 who started the programme and had follow-up data available was 9.4 kg (8.3%), with a mean weight loss of 10.3 kg (9.3%) among the 945 who completed the programme. Amongst the 945 who completed the programme and had two HbA1c measurements, 32% achieved remission, with mean weight loss of 15.9 kg (14.4%), while overall 27% of those who started the programme achieved remission regardless of whether they completed. Remission rates are lower than in trials such as DiRECT and DIADEM-I, despite similar levels of weight loss. The authors highlight that an additional 17% of participants met the HbA1c targets for remission but continued on metformin and may otherwise have achieved remission. These early results confirm that type 2 diabetes remission is indeed possible at scale in the real world, outside of clinical trials.