Place of Total Self-Skin Transplant in the Management of Burns in Children: Results and Predictive Factors

Fatoumata Binta Balde1*, Zineb Benmassaoud1, Thierry Mukenge1, Majdouline Zemmari1, Hicham Abdellaoui1,2, Tazi Mohammed Charki1,2, Karima Atarraf1,2, My Abderrahmane Afifi1,2

1 Department of Pediatric Surgery, Hassan II University Hospital, Fez, Morocco

2 Faulty of Medecine and Pharmacy, Sidi Mohamed Ben Abdallah University, Faz, Morocco

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How to cite this paper: Balde, F.B., Benmassaoud, Z., Mukenge, T., Zemmari, M.,Abdellaoui, H., Charki, T.M., Atarraf, K. and Afifi, M.A. (2021) Place of Total Self-Skin Transplant in the Management of

Burns in Children: Results and Predictive Factors. Open Journal of Pediatrics, 11, 676-683.

https://doi.org/10.4236/ojped.2021.114063

Received: October 10, 2021

Accepted: December 5, 2021

Published: December 8, 2021

Copyright © 2021 by author(s) and Scientific Research Publishing Inc.

This work is licensed under the Creative Commons Attribution International

Abstract

Introduction: Skin transplant is essential in the management of skin substance losses, especially in deep burns. Our work aims to present, through a series of cases, the results of the skin self-transplant carried out to supplement the treatment of skin burns.

Materials and Methods: A one-year prospective study of the total self-skin transplant performed in the management of burns in children was included. After clinic and biologic considerations, a total self-skin transplant was performed.

Results: Forty-five burns were hospitalized, of which six patients received a total self-skin transplant. The average age was 7.43 years with male predominance. The burns were deep thermal burns, preferentially located on the trunk and upper limbs covering over 10% - 25% of the body surface of which 3% - 13% was transplanted. Transplant held in all patients. The surfaces left in spontaneous healing took at least 6 months to heal with some complications. Discussion: We performed a total self-skin transplant beyond technical reasons, for the best aesthetic and functional result it offers. The transplant significantly reduced the healing time with better aesthetic and functional results. The burned surfaces left to direct healing took an average of 6 months to heal and there were associated complications such as formation of keloid scars, hypertrophic plaques and skin retractions leading to cosmetic deformities. The final results appear to be independent of the time required to complete the transplant, and it will be necessary to ensure that there is no local and systemic infection and anaemia.

Conclusion: Total self-skin grafting still has its place in the initial management of burns in children. It offers good aesthetic and functional results. License (CC BY 4.0).

Keywords

Skin Transplant, Burn, Child

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负压封闭引流(VSD)联合间断快速冲洗技术在 下肢开放性骨折合并软组织缺损中的应用研究

龙奇军1 ，杨梅春2* ，杨 娟3 ，黄丽珍1 ，张钰婷1

1 右江民族医学院，广西 百色

2 右江民族医学院附属医院，广西 百色

3 右江民族医学院重金属与氟砷毒物研究实验室，广西 百色

收稿日期：2021年3月19日；录用日期：2021年4月15日；发布日期：2021年4月22日

摘 要

目的：探讨负压封闭引流(VSD)联合间断快速冲洗技术在下肢开放性骨折合并软组织缺损的应用研究。

方法：选取我院创伤骨科2020年1月~2020年10月收治的50例下肢开放性骨折合并软组织缺损行VSD负压引流术后的患者，分为实验组25例用生理盐水快速间断冲洗创面及对照组25例用生理盐水持续冲洗创面，分别对两组护理效果进行比较。通过记录每例发生引流管堵塞的次数、患者疼痛指数评分、使用VSD平均治疗时间、创面愈合效果及疗效显现时间、出院患者满意度进行对比。结果：VSD负压引流术后采用间断冲洗与持续冲洗防止引流管管道堵塞的效果无差别(P > 0.05)，实验组的疼痛程度低于对照组(P <0.05)，实验组使用VSD平均治疗时间短于对照组，实验组创面愈合效果优于对照组(P < 0.05)，实验组疗效显现时间短于对照组(P < 0.05)，实验组的满意度高于对照组(P < 0.05)。结论：负压封闭引流(VSD)联合间断快速冲洗技术能显著促进下肢开放性骨折合并软组织缺损创面的愈合，降低患者的疼痛程度，缩短治疗时间，提高患者满意度，值得推广应用。

关键词：负压封闭引流，VSD，间断快速冲洗，下肢开放性骨折，软组织缺损

文章引用: 龙奇军, 杨梅春, 杨娟, 黄丽珍, 张钰婷. 负压封闭引流(VSD)联合间断快速冲洗技术在下肢开放性骨折合并软组织缺损中的应用研究[J]. 临床医学进展, 2021, 11(4): 1762-1767. DOI: 10.12677/acm.2021.114253

Study on the Application of Negative Pressure Sealed Drainage (VSD) Combined with Intermittent Rapid Irrigation in the Treatment of Open Fractures of Lower Limbs Complicated with Soft Tissue Defects

Qijun Long1, Meichun Yang2*, Juan Yang3, Lizhen Huang1, Yuting Zhang1

1 Youjiang Medical University for Nationalities, Baise Guangxi

2 Affiliated Hospital of Youjiang Medical University for Nationalities, Baise Guangxi

3 Heavy Metal and Arsenic Fluoride Research Laboratory, Youjiang Medical College for Nationalities, Baise Guangxi

Received: Mar. 19th, 2021; accepted: Apr. 15th, 2021; published: Apr. 22nd, 2021

Abstract

Objective: To investigate the application of negative pressure closed drainage (VSD) combined with intermittent rapid irrigation in the treatment of open fractures of lower limbs complicated with soft tissue defects. Methods: A total of 50 patients with open fractures of lower extremity combined with soft tissue defects admitted to the Department of Trauma and Orthopedics of our hospital from January 2020 to October 2020 were selected after VSD negative pressure drainage. The patients were divided into the experimental group (n = 25) and the control group (n = 25), who were rapidly and discontinuously irrigated with normal saline. The nursing effects of the two groups were compared respectively. The frequency of blockage of drainage tube, pain index score of patients, average treatment time with VSD, wound healing effect and curative effect appearance time, and satisfaction of discharged patients were recorded. Results: After VSD negative pressure drainage by intermittent flush with continuous irrigation to prevent drainage pipe blockage effect difference (P > 0.05), the experimental group level of pain is lower than the control group (P <0.05), the experimental group used the VSD treatment time is shorter than the control group on average, the experimental group wound healing effect is better than that of control group (P <0.05), the experimental group curative effect appears shorter than the control group (P < 0.05), the satisfaction degree of the experimental group is higher than control group (P < 0.05). Conclusion: The technique of negative pressure sealed drainage (VSD) combined with intermittent rapid irrigation can significantly promote the wound healing of lower extremity open fracture combined with soft tissue defect, reduce the pain degree of patients, shorten the treatment time and improve patient satisfaction, which is worthy of promotion and application.

Keywords

Negative Pressure Closed Drainage, VSD, Intermittent Quick Washing, Open Fractures of Lower Limbs, Soft Tissue Defect

Copyright © 2021 by author(s) and Hans Publishers Inc.

This work is licensed under the Creative Commons Attribution International License (CC BY 4.0).

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VSD负压引流联合纳米银敷料治疗3、4期 压力性损伤中的应用对比研究

许洋洋* ，陈树荣，田章萍，蔡晓燕，李 慧

盐城市亭湖区人民医院，江苏 盐城

收稿日期：2022年3月26日；录用日期：2022年4月21日；发布日期：2022年4月28日

摘 要

目的：研究VSD负压引流联合纳米银敷料在3、4期压力性损伤感染创面中的应用效果，为3、4期压力性损伤感染创面的患者制定合理的护理方案、评价护理效果提供依据。方法：选取2019年3月~2021年3月一年时间中，在我院就诊的3、4期压力性损伤患者320例，并将其平均分为两组，即观察组与对照组。前者采用的治疗方式为VSD负压引流技术联合纳米银离子敷料；后者使用VSD负压引流技术进行治疗。两组进行数据对比，对比的因素有临床治疗效果、换药次数与费用、创面愈合与肉芽组织生长时间。结果：观察组上述因素都明显低于对照组(P < 0.05)，其临床治疗有效率(86.88%)显著高于对照组(59.38%,P < 0.05)。结论：采用VSD负压引流技术联合银离子技术对3、4期压力性损伤患者进行治疗，可以减少换药次数以此来节省费用，同时患者所承受的疼痛也有很大程度降低，并且创面愈合速度更快，综上所述，其临床应用价值较高，值得进行推广。

关键词

VSD负压引流，纳米银敷料治疗，压力性损伤，促进创面愈合，临床治疗效果，应用对比研究

文章引用: 许洋洋, 陈树荣, 田章萍, 蔡晓燕, 李慧. VSD 负压引流联合纳米银敷料治疗 3、4 期压力性损伤中的应用对比研究[J]. 临床医学进展, 2022, 12(4): 3529-3534. DOI: 10.12677/acm.2022.124512

Comparative Application Study of VSD Negative Pressure Drainage Combined with Nano-Silver Dressing in the Treatment of Stage 3 and 4 Pressure Injuries

Yangyang Xu*, Shurong Chen, Zhangping Tian, Xiaoyan Cai, Hui Li

People’s Hospital of Tinghu District, Yancheng City, Yancheng Jiangsu

Received: Mar. 26th, 2022; accepted: Apr. 21st, 2022; published: Apr. 28th, 2022

Abstract

Objective: To study the application effect of VSD negative pressure drainage combined with nano-silver dressing in stage 3 and 4 pressure injury infected wounds, so as to provide basis for formulating reasonable nursing plan and evaluating nursing effect for patients with stage 3 and 4 pressure injury infected wounds. Methods: A total of 320 patients with stage 3 and 4 stress injury admitted to our hospital from March 2019 to March 2021 were randomly divided into observation group and control group, with 160 cases in each group. The control group was treated with VSD negative pressure drainage, and the observation group was treated with VSD negative pressure drainage combined with nano-silver ion dressing. Pain degree, dressing change times, dressing change cost, wound healing time, granulation tissue growth time and clinical treatment effect were compared between the two groups. Results: The number of dressing change, cost of dressing change, wound healing time, pain degree and granulation tissue growth time in the observation group were significantly lower than those in the control group (P < 0.05). The clinical effective rate in the observation group (86.88%) was significantly higher than that in the control group (59.38%, P < 0.05). Conclusion: We use VSD negative pressure drainage technology to combine silver ion technology to treat patients with stress injuries 3 and 4, which can reduce the number of changes to save costs large extent, and the wound healing is faster, at the same time, the pain of the patient has been greatly reduced, and the wound healing is faster. In summary, its clinical application is worth promoting.

Keywords

VSD Negative Pressure Drainage, Nano-Silver Dressing Treatment, Pressure Injury, Promote Wound Healing, Clinical Treatment Effect, Comparative Application Study

Copyright © 2022 by author(s) and Hans Publishers Inc.

This work is licensed under the Creative Commons Attribution International License (CC BY 4.0).

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Application of Negative Pressure Manual Dressing Change Combined with Mupirocin Ointment in the Treatment of a Case of a Patient with Cirrhosis Complicated with Deep Thigh Abscess

Yingying Meng1,2, Wali Lukman Ahmed3, Jian Luo4*

1 Medical School of Yangtze University, Jinzhou, China

2 Department of Gastroenterology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China

3 Xuzhou Medical University, Xuzhou, China

4 Nursing Department, Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China

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How to cite this paper: Meng, Y.Y., Ahmed,W.L. and Luo, J. (2020) Application of Negative Pressure Manual Dressing Change Combined with Mupirocin Ointment in the Treatment of a Case of a Patient with Cirrhosis Complicated with Deep Thigh Abscess. Journal of Biosciences and Medicines, 8, 113-121. https://doi.org/10.4236/jbm.2020.85011

Received: March 13, 2020

Accepted: May 5, 2020

Published: May 8, 2020

Copyright © 2020 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0).

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Abstract

Objective: To explore the treatment and nursing characteristics for pressure injury on the inside of the thigh caused by forced posture in patients with cirrhosis and diabetes mellitus.

Methods: A patient with cirrhosis and diabetes mellitus complicated with abscess of right inner thigh pressure injury was selected as the study object, who was admitted to Xuzhou Medical University Hospital on June 29, 2019. The analysis of the clinical diagnosis, treatment and nursing process were applied to explore the prognosis of the patient with cirrhosis and diabetes mellitus complicated with deep abscess of the thigh.

Results: The traditional treatment including incision and drainage was not allowed, as the general treatment was not effective for the patients with cirrhosis and diabetes mellitus complicated with deep abscess in the inner thigh. After 8 days of negative pressure manual dressing change combined with mupirocin ointment treatment, the local skin condition returned to normal.

Conclusion: After literature search, it was found that the above-mentioned cirrhosis combined with diabetes and deep abscess cases in the inner thigh were rare clinically. When the traditional treatment of incision and drainage is limited, negative pressure manual dressing change combined with antibiotics is an effective method, which is worthy of clinical application and promotion.

Keywords

Cirrhosis, Diabetes Mellitus, Pressure Injury, Deep Tissue Abscess, Negative Pressure Dressing Change

老年糖尿病患者合并衰弱综合征的研究现状

敏1* ，刘倩倩2 ，王 茹3# ，袁雅倩1

1 武汉科技大学医学院，湖北 武汉

2 三峡大学第三临床医学院国药葛洲坝中心医院心血管内科，湖北 宜昌

3 武汉科技大学附属华润武钢总医院老年病科，湖北 武汉

收稿日期：2022年1月21日；录用日期：2022年2月11日；发布日期：2022年2月24日

摘 要

随着人们年龄的增长，不可避免地出现机体各项生理功能下降，慢性病发生率上升，逐渐走向衰弱，直至生命终结。机体衰弱和糖尿病通常同时出现在某些老年人，且有部分共同的发病机制和危险因素。这篇文章旨在综述近年来对两种病理情况的新认识，描述它们的相互关系研究和治疗策略进展。

关键词

老年化，糖尿病，衰弱，发病机制，相互关系

文章引用: 曾敏, 刘倩倩, 王茹, 袁雅倩. 老年糖尿病患者合并衰弱综合征的研究现状[J]. 临床医学进展, 2022, 12(2):

1366-1373. DOI: 10.12677/acm.2022.122198

Research Status of the Elderly Diabetic Patients with Debilitating Syndrome

Min Zeng1*, Qianqian Liu2, Ru Wang3#, Yaqian Yuan1

1 Medical College, Wuhan University of Science and Technology, Wuhan Hubei

2 Department of Cardiovascular Medicine, Sinopharm Gezhouba Central Hospital, The Third Clinical Medical College of China Three Gorges University, Yichang Hubei

3 Department of Geriatrics, China Resources & WISCO General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan Hubei

Received: Jan. 21st, 2022; accepted: Feb. 11th, 2022; published: Feb. 24th, 2022

Abstract

With the growth of people’s age, it is inevitable that the physiological function of the body declines,and the incidence of chronic diseases increases, and gradually weakened, until the end of life. Frailty and diabetes mellitus usually occur simultaneously in some elderly people, and share some common pathogenesis and risk factors. This article aims to review new insights into two pathological conditions in recent years and describe their interrelationship research and advances in therapeutic strategies.

Keywords

Aging, Diabetes Mellitus, Frailty, Pathogenesis, Relationship

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LncRNAs在糖尿病肾病中的功能及意义研究进展

代丽霞1* ，陈新田1 ，李振江2 ，朱燕亭2#

1 西安医学院，陕西 西安

2 陕西省人民医院肾病血透中心，陕西 西安

收稿日期：2021年12月28日；录用日期：2022年1月18日；发布日期：2022年1月29日

摘 要

糖尿病肾病是糖尿病重要的微血管并发症，引起持续进展的慢性肾脏损害，导致肾功能衰竭。糖尿病肾病作为慢性肾病患者主要病因及死亡原因，极大地加重了全球健康及经济负担。糖尿病肾病发病机制较为复杂，现有治疗方案效果有限，亟待进一步探索发病机制，以更好地预防、治疗、管理糖尿病肾病。长链非编码RNA参与了许多生理过程，如细胞周期调节、细胞凋亡和存活、肿瘤迁移和代谢等。某些LncRNAs在糖尿病肾病发病机制中发挥重要作用。本文综述了参与糖尿病肾病发病机制、作为生物标志物或在临床应用中作为治疗靶点的LncRNAs。

关键词

糖尿病肾病，LncRNAs，生物标志物，治疗靶点

Progress in the Function and Significance of LncRNAs in Diabetic Nephropathy Lixia Dai1*, Xintian Chen1, Zhenjiang Li2, Yanting Zhu2#

1 Xi’an Medical University, Xi’an Shaanxi

2 Kidney Disease Hemodialysis Center of Shaanxi Provincial People’s Hospital, Xi’an Shaanxi

Received: Dec. 28th, 2021; accepted: Jan. 18th, 2022; published: Jan. 29th, 2022

Abstract

      Diabetic nephropathy (DN) is a major microvascular complication of diabetes mellitus, leading to gradual progress in chronic deterioration of renal function, eventually resulting in the occurrence of kidney failure. DN is the major cause of the high morbidity and mortality of chronic kidney disease (CKD), which significantly aggravates the healthy and economic burden globally. Therefore, it is important to explore the underlying mechanism for prevention and management of DN due to the complicated pathogenesis and limited therapy. Long noncoding RNA (LncRNA), a novel target, is involved in many physiological processes, such as cell cycle regulation, apoptosis, cell survival, tumor migration and metabolism. Furthermore, evidence suggests that LncRNAs play a vital role in DN pathogenesis. This review summarizes LncRNAs, which are involved in the pathogenesis of DN, and used as biomarkers or therapeutic targets of DN in clinical practice.

Keywords

Diabetic Nephropathy, LncRNAs, Biomarkers, Therapeutic Targets

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