伤口世界

Diabetes remission in the real world 2024-09-20 00:00

Pam Brown

GP in Swansea

Citation: Brown P (2024) Diabetes Distilled: Diabetes remission in the real world. Diabetes & Primary Care 26: 145–7

Diabetes remission is achievable at scale in the real world, according to early results from the NHS Type 2 Diabetes Path to Remission programme published in Lancet Diabetes & Endocrinology. Of 7540 people referred to the programme between September 2020 and December 2022, a total of 1740 started the total diet replacement section of the programme before January 2022, and 960 (55%) completed the programme. Mean weight loss for the 1710 who started the programme and had follow-up data available was 9.4 kg (8.3%), with a mean weight loss of 10.3 kg (9.3%) among the 945 who completed the programme. Amongst the 945 who completed the programme and had two HbA1c measurements, 32% achieved remission, with mean weight loss of 15.9 kg (14.4%), while overall 27% of those who started the programme achieved remission regardless of whether they completed. Remission rates are lower than in trials such as DiRECT and DIADEM-I, despite similar levels of weight loss. The authors highlight that an additional 17% of participants met the HbA1c targets for remission but continued on metformin and may otherwise have achieved remission. These early results confirm that type 2 diabetes remission is indeed possible at scale in the real world, outside of clinical trials.
Impact of metformin timing on glucose and GLP-1 response 2024-09-19 00:00

Pam Brown GP in Swansea

Citation: Brown P (2024) Diabetes Distilled: Impact of metformin timing on glucose and GLP-1 response. Diabetes & Primary Care 26: 143–4

Glucose-lowering effects in response to normal-release metformin are greater when the drug is given 30 or 60 minutes before, rather than with, food, according to this small study in people with well-controlled type 2 diabetes published in Diabetologia. Endogenous GLP-1 secretion increased when metformin 1000 mg was given 30 or 60 minutes prior to a glucose infusion, whereas there was no increase when the metformin was administered at the same time as the glucose. The results suggest that, if tolerated, administering standard release metformin before meals may lead to improved postprandial glycaemic control.
The importance of getting the correct diabetes diagnosis 2024-09-18 00:00

Jane Diggle Specialist Diabetes Nurse Practitioner, West Yorkshire

Citation: Diggle J (2024) The importance of getting the correct diabetes diagnosis. Diabetes & Primary Care 26: 111–2

Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

伤口世界

续集：斑块旋切系统+药物洗脱外周球囊扩张导管治疗后创面的处理

《首例股腘动脉闭塞TurboHawk斑块旋切系统+药物洗脱外周球囊扩张导管治疗》中报告的病例，虽然血管做得非常成功，但是最后糖尿病足的完全痊愈却还经过了十分艰辛的过程，也突出了糖尿病足发病机理的复杂及治疗的困难。

创伤负压治疗技术在糖尿病足病中的应用

糖尿病下肢血管病变的挑战和应对

糖尿病下肢动脉病变腔内（介入）治疗

足部的慢性伤口患者注意事项：

痛风患者如何选择饮食疗法？

学术会议

伤口世界提示

Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

伤口世界

续集：斑块旋切系统+药物洗脱外周球囊扩张导管治疗后创面的处理

《首例股腘动脉闭塞TurboHawk斑块旋切系统+药物洗脱外周球囊扩张导管治疗》中报告的病例，虽然血管做得非常成功，但是最后糖尿病足的完全痊愈却还经过了十分艰辛的过程，也突出了糖尿病足发病机理的复杂及治疗的困难。

创伤负压治疗技术在糖尿病足病中的应用

糖尿病下肢血管病变的挑战和应对

糖尿病下肢动脉病变 腔内（介入）治疗

足部的慢性伤口患者注意事项：

痛风患者如何选择饮食疗法？

消息订阅

学术会议

伤口世界提示

糖尿病下肢动脉病变腔内（介入）治疗